Protein Alignment Cyp4d2 and LOC1277762

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_317256.4
• Gene: LOC1277762 / 1277762
• VectorBaseID: AGAMI1_002278
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 1188
• Identity: 231/1188 - (19%)
• Similarity: 387/1188 - (32%)
• Gaps: 450/1188 - (37%)

  Fly    33 NGIRVLLVSDPTTDKSAAALDVKVGHLMDP---WEL-----PGLAHFCEHMLFLGTAKYPSENEY 89
            ||.|.:|....|......||.::|.|...|   :.|     ||...:.:..:.|.|:::..:|:.
Mosquito  2274 NGYRSILSEKFTLTPGVQALKLRVEHKTKPTFYYNLGVEVRPGTGRYKDTQVVLLTSRFLLQNQS 2338

  Fly    90 SKFLA-------------AHAGSSNAYTSSDHTNY---------HFDVKPDQLPGALDRFVQFFL 132
            :..|:             .|..:.::.|.::  ||         ..|||....|..:||...|.:
Mosquito  2339 TVALSVCHHDLVEMEKDHVHLAAQSSTTWNE--NYAGRRMLCVRRADVKHWSCPFLIDRIGSFHV 2401

  Fly   133 -------SPQF---------------------------------------TESATE-----REVC 146
                   :|:|                                       .||:|.     |.:|
Mosquito  2402 TMRDADETPRFIRVEIILTSAVFQITFTNADLYPPPIRIENLTDVPVLYQQESSTPARPHLRTIC 2466

  Fly   147 --------AVDSEHSNNLNNDLWRFLQVDRSRSK------PG----------------HDY---- 177
                    |.|..:.|..     ..|||..:|||      ||                |.:
Mosquito  2467 KSRSVVDYAWDDLYGNKK-----MVLQVFENRSKSYEISLPGPAEPLVYENSSYIQLAHSFTKRS 2526

  Fly   178 GKFGTG---NKQTLLEDARKKGIEPRDALLQFHKKWYSSDIMTCCIVG---------------KE 224
            || |:|   ::|.|:.:..:||    ..:|....:...:.:...|..|               :.
Mosquito  2527 GK-GSGEFTDEQELVLETMQKG----KVMLNKQCRTEDNQLWKLCADGCIENVGMNHRKRSDSRL 2586

  Fly   225 PLNVLESYLGTL---EFDAIENKKVERKVWEEFPYGPDQLAKRID----VVPIKDTRLVSISFPF 282
            .|:|||...|.|   |.|...||      |:.:.:.||.....||    ::..|.|..|.:....
Mosquito  2587 VLDVLEKTGGRLMMMERDKRRNK------WQRWTWMPDGRLCLIDSPHLMMTSKQTEAVVVEADG 2645

  Fly   283 PDLNGE-----------FLSQPGHYISHLIG----HEGPGSLLSELKRLGWVSSLQSDSHTQAAG 332
            ....||           ...:||   |..:|    |.|| ::|..:....:.:...|:...|||.
Mosquito  2646 LAPKGEDGVAVTQIWKVQRQRPG---SGTLGVEFLHSGP-TVLIRITDREFQTRAVSEPMIQAAN 2706

  Fly   333 -FGVYNVTMDLS-------TEGLEHVDEIIQLMFNYIGMLQSAGPKQWVHDELAELSAVKFRFKD 389
             ..|.:|::.:.       ..||:  :|:|...|.  |::.||                  |..|
Mosquito  2707 KLAVLDVSITMRGGLGISVVNGLQ--EELIYAHFG--GIVVSA------------------RRVD 2749

  Fly   390 KEQPMTMAINVAASLQYIPFEHILSSRYLLTKYEPERIK----ELLSMLSPANMQVRVVSQKFKG 450
            |...||.:::|.    .|..:.:.|.|:.:...:|:..:    ::|.:  ||.:.|
Mosquito  2750 KTYQMTGSVDVI----QIDNQLLSSDRWQVLYCQPDAGQNYDDQMLEL--PAGIPV--------- 2799

  Fly   451 QEGNTNEPVYGTEMKVTDISPETMKKYEN----ALKTSHHALHLPE----------KNEYIATNF 501
                |..|....||..|     :||.|::    .||....::.|.|          ::...|::.
Mosquito  2800 ----TGRPALKLEMNCT-----SMKHYDSFDCFRLKVCDMSVQLDELLLWKIVQMAQSSDAASSV 2855

  Fly   502 DQK-----PRESVKNEHPR----------------------LISDDGWSRVWFKQDDEYNMPKQE 539
            .|:     |...::...|.                      .:|..|..|       :..:.||:
Mosquito  2856 QQRALNLPPNTELERHDPLRTRRWYFGTLDLEMGHVGLSVVTVSKSGLPR-------DLRLLKQQ 2913

  Fly   540 TKLALTT---PMVAQNP---------RMSLLSSLWLWCLSDTLAEETYN--------ADLAGLKC 584
            ..:.|.:   ..||..|         ...||.||..:.|:: |.::|.:        .:..||..
Mosquito  2914 FNVKLISFENASVALPPFRQYHYFETSSFLLESLQKFYLAE-LQKQTLSIIVTLDAFGNPLGLVT 2977

  Fly   585 QLESS-----------------PFGVQMRVSNRREAERHAS----LTLHVYGYDEKQALFAKHLA 628
            .|:.|                 .:|:...||  :.|...||    ||     :|:...|..:|
Mosquito  2978 DLKDSFQGLFIEGDVQRFVAGLGYGLSNSVS--KVASSMASGVGALT-----FDQDHELKRRH-- 3033

  Fly   629 NRMTNFKIDKTRFDVLFESLK-----------RALTNHAFSQPYLLTQHYNQLLIVDKVWSKEQL 682
            |.:.:.....|....|:..:|           ...||.|       ::.....|:...||.  ..
Mosquito  3034 NMIRSHSSSSTPLTHLYSGVKGLGVGVLGGATAMFTNVA-------SESRKSGLVKGMVWG--VA 3089

  Fly   683 LAVCDSVTLEDVQGFAKEMLQAFHMELFVHGNSTEKEAI-------------------QLSKELM 728
            ..|.|:|| :.|||...          ||.|.::..:.:                   :|.:.|.
Mosquito  3090 TGVVDTVT-KPVQGVFD----------FVEGTASAMKELAMPATGVRRATALCRVRIPRLCRNLY 3143

  Fly   729 DVLKSAAPNSRPLYRNEHNPRRELQLNNGDEYVYRHLQKTHDV-GCVEVTYQIGVQNTYDNAVVG 792
            .:|.:..||..       :.:.||...||    |...::..|| .|:|   .|...|
Mosquito  3144 HLLPAYNPNLA-------HAQMELLRING----YSSREQLLDVETCLE---HIDAAN-------- 3186

  Fly   793 LIDQLIREPAFNTLRTNEALGYIVWTGSRLNCGTVALNVIVQGPKSVDHVLERIEV-FLESVRKE 856
             ||::||:  :..:.|.:.  |:        |..      ..|..|:  |::||.. :|:||
Mosquito  3187 -IDRIIRQ--YVLISTKQC--YV--------CRQ------TNGESSI--VIQRIAYKYLKSV--- 3227

  Fly   857 IAEMPQEEFDNQVSGMIARLEEKPKTLSSRFRRFWNEIECRQYNFARREEEVALLKTIKKDDVLE 921
            :|..|.|   |..|.:...|:.:    .:|.|:.  .:.|.:...|||..:       |.....:
Mosquito  3228 VARPPLE---NTFSSIEVSLDME----DARLRQI--HVWCSRIEVARRLAD-------KMQRAKQ 3276

  Fly   922 LFD--KKIRKDAAERRKL 937
            |:|  |:...|.|..:.|
Mosquito  3277 LYDHNKRTLNDVAWTKSL 3294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	115/601 (19%)
LOC1277762	XP_317256.4	None