Protein Alignment Cyp4d2 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 523
• Identity: 204/523 - (39%)
• Similarity: 307/523 - (58%)
• Gaps: 48/523 - (9%)

  Fly     2 LGVVGVLLLVA-FATLLLWDFLWRRRGNGILPG-PRPLPFLGNLLMYRGLDPEQIMDFVKKNQR- 63
            :.:.|..:|:: |..|:.:...|::..:  :|. .|..|.:|:.|..:..:.|.....:...:.
Mouse    22 VSLAGATILISIFPMLVSYARKWQQMRS--IPSVARAYPLVGHALYMKPNNAEFFQQLIYYTEEF 84

  Fly    64 KYGRLYRVWI--LHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRR 126
            ::..:.::||  :..:|::..:  ::|.:|:|.:.|.|:.|||.|..|||.|||.|||.||..||
Mouse    85 RHLPIIKLWIGPVPLVALYKAE--NVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRR 147

  Fly   127 KIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINA 191
            |::||||||.|||.|:::.::|:.::|.:|:...: ....|.|..|.|.|||||.|||||..|.|
Mouse   148 KMLTPTFHFTILENFLDVMNEQANILVNKLEKHVN-QEAFNCFFYITLCALDIICETAMGKNIGA 211

  Fly   192 QKNPNLPYVQAVNDVTNILIKRFIHAWQRVD-W--IFRLTQPTEAKRQDKAIKVMHDFTENIIRE 253
            |.|.:..||:.|..:::::.:|....|...| |  :|:     |.:...:.:|.:|.||.|:|.|
Mouse   212 QSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFK-----EGRDHKRGLKCLHTFTNNVIAE 271

  Fly   254 RRETLVNNSKETTPEEEVNFLG------QKRRMALLDVLLQST-IDGAPLSDEDIREEVDTFMFE 311
            |       .||...||:....|      :.:|.|.||:||..| .:|..||.|||||||||||||
Mouse   272 R-------VKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFE 329

  Fly   312 GHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHP 376
            |||||.:||::.||.:..:||||:::.||:.:|.|...: ||||.||.:||:::.||||:||:.|
Mouse   330 GHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHR-PVTLEDLKKLKYLDCVIKETLRVFP 393

  Fly   377 PVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQ-IHPYAYI 440
            .||:..|..:||.|:.|..:..||...:..:.|.|||.||..|:|||||||..:..| .|||||:
Mouse   394 SVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGRHPYAYV 458

  Fly   441 PFSAGPRNCIGQKFAMLEMKSTVSKLLRHF--------ELLPLGPEPRHSMNIVLRSANGVHLGL 497
            |||||||||||||||::|.|:.::.:||.|        |.|.|..:      ::||..||:.:.|
Mouse   459 PFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGD------LILRPNNGIWIKL 517

  Fly   498 KPR 500
            |.|
Mouse   518 KRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	190/449 (42%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	190/460 (41%)