Protein Alignment Cyp4d2 and cyp4b1.6

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_002931495.3
• Gene: cyp4b1.6 / 100488386
• XenbaseID: XB-GENE-5864180
• Length: 519
• Species: Xenopus tropicalis
• Alignment Length: 511
• Identity: 182/511 - (35%)
• Similarity: 283/511 - (55%)
• Gaps: 48/511 - (9%)

  Fly     8 LLLVAFATLLLWDFLWRRR---GNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY---- 65
            ||||.:....|  ::|||:   .....|||:.....||  .|..|...:.:|.|....:.:
 Frog    27 LLLVLYKAAQL--YVWRRKLVAAFSPFPGPKCHWLYGN--TYEFLQIGKDLDLVLGWAQVFPYGM 87

  Fly    66 ----GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNL-YKLLNCWLGDGLLMSTGRKWHGR 125
                |..|...|:       |.|...:.||:.|.  .|::: ||.:..|:|:|||:.:|.||...
 Frog    88 PLWLGNFYATLII-------THPDYAKAVLARQD--PKDDMAYKFIVPWIGEGLLVLSGPKWFQH 143

  Fly   126 RKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKIN 190
            |:::||.||:.:|:.:|.:....:.||:::..........:.:|..:.|..||.|.:.|.....:
 Frog   144 RRLLTPGFHYDVLKPYVTLMSDCTRVMLDKWDKLMPNEKSVELFHYVSLMTLDTIMKCAFSYNTS 208

  Fly   191 AQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERR 255
            .|.|.:..|:.||.:::.::.:||.........||.|: |. ..|..||:...|..|:.:|::|:
 Frog   209 CQNNRDNAYINAVYELSYLVDQRFRFFPYHNKLIFHLS-PL-GFRFRKALSTAHQHTDKVIKQRK 271

  Fly   256 ETLVNNSKETTPEEEVNFLGQKRRMALLDVLL-QSTIDGAPLSDEDIREEVDTFMFEGHDTTTSA 319
            |:|::       |.|::.:.|||.:..||:|| ....:|..|||||:|.|||||||||||||.|.
 Frog   272 ESLMH-------ETELDKIRQKRHLDFLDILLCAKDENGKGLSDEDLRAEVDTFMFEGHDTTASG 329

  Fly   320 ISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRW 384
            ||:.||.|:::||.||:.::||.::|||  :..:...|||::.:....|||||||:||||.|||.
 Frog   330 ISWILYCIAKYPEHQQKCREEITELLGE--RETMGWDDLGKIPYTTLCIKESLRLYPPVPGIGRR 392

  Fly   385 FAEDVEI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQ----IHPYAYIPFSA 444
            .::.:.. .|:.:|.|.:..:.|:.:.|.|..::.|:.|.|.||   :|:    .||:|::||||
 Frog   393 LSKPITFCDGRSLPEGASIILSIYSINRSPSLWKDPEVFDPLRF---LPENSDNRHPHAFLPFSA 454

  Fly   445 GPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGP--EPRHSMNIVLRSANGVHLGLK 498
            ||||||||.|||.|||..|:..|:.:||.| .|  ||:....|||||.||:|:.|:
 Frog   455 GPRNCIGQNFAMNEMKVAVALTLQRYELFP-DPDNEPQKVPQIVLRSLNGIHVKLR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	163/437 (37%)
cyp4b1.6	XP_002931495.3	CYP4B-like	73..507	CDD:410771	166/457 (36%)