DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d1 and CYP96A4

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_200045.1	Gene:	CYP96A4 / 835308	AraportID:	AT5G52320	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	124/548 - (22%)
Similarity:	233/548 - (42%)	Gaps:	90/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLVIGAILASALFVGLLLY-----HLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKK 60
            |.::||.:.....|:...:|     |.|..:  .::...|...:||    |..|       .:.:
plant     1 MAMIIGLLEIFIAFIFFFVYQCFSLHKKTPK--HMVMNWPVLGMLP----GVLF-------QIPR 52

  Fly    61 IFEFM-ETYSKDQVLKVWLGPELN----VLMGNPKDVEVVLGTLRFN-DKAGEYKALEPWLKEGL 119
            |::|: |....:.:...::||.|:    :|..:|.:::.:|.:...| .|..::..:..:|.:|:
plant    53 IYDFVTEALEAENMTGCFIGPWLSGTDILLTVDPVNIQYILSSNFVNYPKGKKFNKIFEFLGDGI 117

  Fly   120 LVSRGRKWHKRRKIITPAFHFKILDQF-----VEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWI 179
            .......|...|......|..:....|     |....:|...:|.|..:..:.     ..|.|..
plant   118 FNVDSGLWEDMRNSSHAIFSHQDFQSFSVSTSVSKLSQGLVPILDNAVEKHIL-----VDLQDLF 177

  Fly   180 NLCTMDTICETAMGVSINAQS--NADSEYVQAVKTISMVLHKRMFNILYRFDL-TYMLTPLARAE 241
            .....||......|....:.|  ....|:..|:..::..:..|.....:.:.: :::...:.:..
plant   178 QRFLFDTSSTLMAGYDPKSLSVEMPKVEFADAMDGVADAMFYRHLKPAFLWSIQSWIGVGIEKKM 242

  Fly   242 KKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE------RP 300
            ::.|:|..|...|||..:|||:...| ..:|..:..||          :....|:|.      :|
plant   243 RRGLDVFDQMLGKIISAKREEIKNHG-IHDSKGEAMDV----------LTYYMTIDTTKYKHLKP 296

  Fly   301 LSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQ 365
            .::..||:.:...:....|||||||.:||:.::.:|||..|..:||     |.|........|::
plant   297 SNDKFIRDTILGLVIAARDTTSSALTWFFWLLSKNPEAMTKIRQEI-----NKKMPKFDPADLDK 356

  Fly   366 LHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGK------LIPAGTNIG-----ISPLY-LGRRE 418
            |.|:|..|.||||:|||||           .|.|      ::|:|..:.     :.|:| |||.:
plant   357 LVYLDGAVCETLRLYPSVP-----------FNHKSPAKPDVLPSGHKVDKNWRVVIPIYSLGRMK 410

  Fly   419 ELF-SEPNIFKPERFDVVTTAEKL---NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEV 479
            .:: .:...|:|||:  ::.:..|   :.|.::.|:||||.|:|::...|::|.:...::|:|::
plant   411 SVWGDDAEDFRPERW--ISDSGMLRQESSYKFLAFNAGPRTCLGKRLTFLQMKTVAVEIIRNYDI 473

  Fly   480 DFVGDSSEPPVLIAELILRTKEPLMFKV 507
            ..|......||  ..::||.:..|...|
plant   474 KVVEGHKPKPV--PSVLLRMQHGLKVSV 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	116/507 (23%)
CYP96A4	NP_200045.1	p450	1..501	CDD:416425	124/548 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920