DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d1 and CYP714A1

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_568463.1	Gene:	CYP714A1 / 832560	AraportID:	AT5G24910	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	113/547 - (20%)
Similarity:	224/547 - (40%)	Gaps:	75/547 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LVIGAI-LASALFVGLLLYHLKFKRLIDLISYMPGPPVL-------------PLVGHGHHFIGKP 53
            :|||.: |...::..::....:.:|.:.:......||.|             .::.:..|:.|..
plant    16 VVIGVLGLGIRVYGKVMAEQWRMRRKLTMQGVKGPPPSLFRGNVPEMQKIQSQIMSNSKHYSGDN 80

  Fly    54 --PHEMVKKIFEFMETYSKD--QVLKVWLGPELNVLMGNPKDVEVV--LGTLRFNDKAGEYKALE 112
              .|:....:|.:::.:.|.  :|.....|.:.::.|.:|:.|:.:  ..||.....:...|.|:
plant    81 IIAHDYTSSLFPYLDHWRKQYGRVYTYSTGVKQHLYMNHPELVKELNQANTLNLGKVSYVTKRLK 145

  Fly   113 PWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLY- 176
            ..|..|::.|.|..|..:|:||.|.|....:...|.:..:.:..:|...|:...:.|:....:.
plant   146 SILGRGVITSNGPHWAHQRRIIAPEFFLDKVKGMVGLVVESAMPMLSKWEEMMKREGEMVCDIIV 210

  Fly   177 -DWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARA 240
             :.:...:.|.|.....|.|.:......|:.....|.|:   |.   |||:..:   ..|.:...
plant   211 DEDLRAASADVISRACFGSSFSKGKEIFSKLRCLQKAIT---HN---NILFSLN---GFTDVVFG 266

  Fly   241 EKK----ALNVLHQFTEKII---VQRRE------------ELIREGSSQESSNDDADVGAKRKMA 286
            .||    .::.|.:..|.:|   |:.||            :||.||:......:..|.....|..
plant   267 TKKHGNGKIDELERHIESLIWETVKERERECVGDHKKDLMQLILEGARSSCDGNLEDKTQSYKSF 331

  Fly   287 FLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVG 351
            .:|                   ...:..|.||:|::.|:.:....:|.:|..|.:..:|   |..
plant   332 VVD-------------------NCKSIYFAGHETSAVAVSWCLMLLALNPSWQTRIRDE---VFL 374

  Fly   352 NDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGR 416
            :.|:.....:.::.|..|.:.::||||:||....:.|:.|||.::...::|.|..|......|.|
plant   375 HCKNGIPDADSISNLKTVTMVIQETLRLYPPAAFVSREALEDTKLGNLVVPKGVCIWTLIPTLHR 439

  Fly   417 REELF-SEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVD 480
            ..|:: ::.|.|.||||....:....:|.:::||..|.|.|:|:.|.|:|:|.:|:.::..:...
plant   440 DPEIWGADANEFNPERFSEGVSKACKHPQSFVPFGLGTRLCLGKNFGMMELKVLVSLIVSRFSFT 504

  Fly   481 FVGDSSEPPVLIAELILRTKEPLMFKV 507
            ........||.  .:::..:..::.:|
plant   505 LSPTYQHSPVF--RMLVEPQHGVVIRV 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	107/512 (21%)
CYP714A1	NP_568463.1	p450	37..530	CDD:299894	109/526 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960