DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and TT7

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_196416.1	Gene:	TT7 / 830693	AraportID:	AT5G07990	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	135/567 - (23%)
Similarity:	237/567 - (41%)	Gaps:	123/567 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISY----MPGPPVLPLVGHGHHFIGKPPHEMVKKI 61
            :||.|  :||:.||:.|.::..:..|     |:    .|||...|::|:..| :|..||   :.:
plant     4 LFLTI--LLATVLFLILRIFSHRRNR-----SHNNRLPPGPNPWPIIGNLPH-MGTKPH---RTL 57

  Fly    62 FEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLK--EGLLVSR- 123
            ...:.||          ||.|::.:|   .|:||:        |......|.:||  :....||
plant    58 SAMVTTY----------GPILHLRLG---FVDVVV--------AASKSVAEQFLKIHDANFASRP 101

  Fly   124 --------------------GRKWHKRRKIIT-PAFHFKILDQFVEVFEKGSRDLLRNMEQDRLK 167
                                |.:|...|||.: ..|..|.|:.|..|.::....|.|.:    ::
plant   102 PNSGAKHMAYNYQDLVFAPYGHRWRLLRKISSVHLFSAKALEDFKHVRQEEVGTLTREL----VR 162

  Fly   168 HGDSGFSLYDWINLCTMDTICETAMGVSI-NAQSNADSEYVQAVKTISMVLHKRMFNI------L 225
            .|....:|...:|:|.::.:....:|..: .|.::..::..:::.|..|.| ..:|||      |
plant   163 VGTKPVNLGQLVNMCVVNALGREMIGRRLFGADADHKADEFRSMVTEMMAL-AGVFNIGDFVPSL 226

  Fly   226 YRFDLTYMLTPLARAEKKALNVLHQFTEKIIV--------QRREELIREGSSQESSNDDADVGAK 282
            ...||..:...:.|..|:    ...|...|:.        |:..:::....|.:.::.|.|.|:
plant   227 DWLDLQGVAGKMKRLHKR----FDAFLSSILKEHEMNGQDQKHTDMLSTLISLKGTDLDGDGGS- 286

  Fly   283 RKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIR 347
                              |::.:|:..:......|.||::|.:.:....:..||:...|..||:.
plant   287 ------------------LTDTEIKALLLNMFTAGTDTSASTVDWAIAELIRHPDIMVKAQEELD 333

  Fly   348 SVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPL-LGRKVLEDCEINGKLIPAGTNIGISP 411
            .|||.|:  ||:...:.||.|:...:||..|::|..|| |.....|.|||||..||.|:.:..:.
plant   334 IVVGRDR--PVNESDIAQLPYLQAVIKENFRLHPPTPLSLPHIASESCEINGYHIPKGSTLLTNI 396

  Fly   412 LYLGRREELFSEPNIFKPERF---------DVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIK 467
            ..:.|..:.:|:|..||||||         ||     |.:.:..|||.||.|.|.|....:..|:
plant   397 WAIARDPDQWSDPLAFKPERFLPGGEKSGVDV-----KGSDFELIPFGAGRRICAGLSLGLRTIQ 456

  Fly   468 AIVANVLRHYEVDFVGDSSEPPVLIAE---LILRTKEPLMFKVRERV 511
            .:.|.:::.::.:..|..:...:.:.|   |.|:...||:...:.|:
plant   457 FLTATLVQGFDWELAGGVTPEKLNMEESYGLTLQRAVPLVVHPKPRL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	124/523 (24%)
TT7	NP_196416.1	PLN02687	2..511	CDD:215371	135/567 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910