DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP706A6

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_192969.4	Gene:	CYP706A6 / 826841	AraportID:	AT4G12320	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	123/504 - (24%)
Similarity:	215/504 - (42%)	Gaps:	77/504 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNP-------KDV 92
            |||..||:||: ..|:....|....|:.|     |...:.|:.||.:|.|::..|       ||.
plant    44 PGPRGLPIVGN-LPFLDPDLHTYFTKLAE-----SYGPIFKLNLGSKLTVVVNTPSLAREILKDQ 102

  Fly    93 EVVLGT--LRFNDKAGEYKALE-PWLKEGLLVSRGRKWHKRRKI-ITPAFHFKILDQFVEVFEKG 153
            ::....  :....:|..|..|: .||      ..|.:|...||: :......:.|:.|.|:..|.
plant   103 DINFSNHDVPLTARAVTYGGLDLVWL------PYGAEWRMLRKVCVLKLLSHRTLNSFYELRRKE 161

  Fly   154 SRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQ--SNADSEYVQAVKTISMV 216
            .|:..|.:.|...:  :|..::.:.:.|..|:.......|.|:.|:  .:..:|:.:.:..|:.:
plant   162 IRERTRYLYQKGQE--ESPVNVGEQVFLTMMNLTMNMLWGGSVKAEEMESVGTEFKEVISEITRL 224

  Fly   217 LHK----RMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDA 277
            |.:    ..|..|.||||..::..:....::...:|.:..|::.:.|    .|:|...|..:
plant   225 LGEPNVSDFFPRLARFDLQGLVKKMHVCARELDAILDRAIEQMQLLR----TRDGDDGECKD--- 282

  Fly   278 DVGAKRKMAFLDILL----QSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEA 338
                     ||..|:    |....|.|::...::..:...:..|.||:::.:.|....:...||.
plant   283 ---------FLQHLMKLKDQEADSEVPITVNHVKAVLVDLVVGGTDTSTNTIEFAMAELIRKPEL 338

  Fly   339 QKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLL-GRKVLEDCEINGKLIP 402
            .|:..:|:..|||.|.....|:  :.:|.::...:|||||:||::||| ..:..|...:.|..||
plant   339 MKRAQQELDEVVGKDNIIEESH--ITRLPFISAIMKETLRLYPTIPLLVPHRPSETALVGGYTIP 401

  Fly   403 AGTNIGISPLYLGRREELFSEPNIFKPERF------DVVTTAEKLNPYAYIPFSAGPRNCIGQKF 461
            ..|.|.|:...:.|...::..|..|:||||      |...|     .|:|:||.:|.|.|.|...
plant   402 KNTKIFINVWSIQRDPNVWEYPTEFRPERFLDKKSCDFTGT-----DYSYLPFGSGRRICAGIAL 461

  Fly   462 AMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL------ILRTKEPLM 504
            |...|...:|.:|..:      |...|...|.:|      :|:.|.||:
plant   462 AERMILYTLATLLHSF------DWKIPEGHILDLKEKFGIVLKLKSPLV 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	123/504 (24%)
CYP706A6	NP_192969.4	p450	17..514	CDD:299894	123/504 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910