DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP71A23

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001325471.1	Gene:	CYP71A23 / 823988	AraportID:	AT3G48300	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	130/534 - (24%)
Similarity:	228/534 - (42%)	Gaps:	90/534 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFM 65
            |.|.:..|:   ||:..:|:..|.|.:..:|:: |.||.|||:|:.|. :.:.||   :.:....
plant     3 MILFLCLII---LFIITILFFKKHKTVNKIINF-PSPPRLPLIGNLHQ-LSQHPH---RSLCYLS 59

  Fly    66 ETYSKDQVLKVWLGPELNVLMGN-----PKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSR-- 123
            ..|          ||.:.:..|:     ....|.....|:.:|:....:......::.|..||
plant    60 HRY----------GPLMLLHFGSVPVIVASTAEAARDVLKTHDRVFASRPRSKIFEKLLYKSRNM 114

  Fly   124 -----GRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCT 183
                 |..|.:.:.:  ...|. :.::.|..|:...::.:..|.:...|......:|...::..|
plant   115 ASAPYGEYWRQMKSV--SVLHL-LSNKMVRSFQDVRQEEITLMMETIRKSSSKPVNLSKILSSLT 176

  Fly   184 MDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDL---------TYMLTPL-A 238
            .|.||..|:|          .:|  .|.|....|..|:...|..|.:         |..::.| |
plant   177 NDVICRVALG----------RKY--GVGTDFKELIDRLMRQLGTFTIGSYVPWLAWTDWVSGLEA 229

  Fly   239 RAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDER---P 300
            |.||.| |...:..|:|:             |:..:.|.|     |..|:|:||.:..|:.   .
plant   230 RLEKTA-NDFDKLLERIV-------------QDHEDGDGD-----KTDFVDVLLAAQRDKSFGFD 275

  Fly   301 LSNLDIREEV-DTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLN 364
            :..|.|:..| |.|: .|.||:|:.:.:....:..||...||..||:|::.....|  ||.:.:.
plant   276 IDRLSIKAIVLDAFV-GGTDTSSTLVEWEMTELLRHPTCLKKLQEEVRTICKGKSS--VSEDDIQ 337

  Fly   365 QLHYVDLCVKETLRMYPSVPLL-GRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFS-EPNIF 427
            .:.|:...|||.||::|.|||: ..:..:|..:....|||||.:.::...:||....:. :.|.|
plant   338 GMEYLKAVVKEALRLHPPVPLMVPHQSTQDVRLRDNHIPAGTQVIVNLWAVGREAATWGPDANEF 402

  Fly   428 KPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLI 492
            :|||.....:..:...:..|||.||.|.|.|..||::..:.::||::..::...:.|.::    :
plant   403 RPERHLESPSDFRGQDFELIPFGAGRRMCPGISFAVVLNEVVLANLVHGFDWQSIDDETD----V 463

  Fly   493 AELI---LRTKEPL 503
            ||.|   :|...||
plant   464 AESIGSVIRRMHPL 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	121/500 (24%)
CYP71A23	NP_001325471.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910