DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP71A25

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_680107.1	Gene:	CYP71A25 / 823986	AraportID:	AT3G48280	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	110/512 - (21%)
Similarity:	212/512 - (41%)	Gaps:	82/512 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LLLYHLKFKRLIDLISYM--------PGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQV 73
            :||:.:.|..::.|...:        |.||.|||:|:.|. :|:..|   :.:.:....|....:
plant     6 ILLWSIIFMTILFLKKQLSGKKGKTPPSPPGLPLIGNLHQ-LGRHTH---RSLCDLSRRYGPLML 66

  Fly    74 LKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSR--------GRKWHKR 130
            |.:...|.|.|     ...::....|:.:|:|...:.... |.:.||.:.        |..|.:.
plant    67 LHLGRVPVLIV-----SSADMAQEILKTHDQAFANRPRSK-LSQKLLYNNRDVASAPYGEYWRQM 125

  Fly   131 RKIITPAFHF---KILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAM 192
            :.:.  ..|.   |::..|.:|.|:   ::...|.:.| |.....|::...:...|.|.||..|:
plant   126 KSVC--VIHLLSNKMVRSFRDVREE---EITLMMAKIR-KSSSLPFNVSKVLECLTNDVICRVAL 184

  Fly   193 GVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAE---------KKALNVL 248
            |.....:::...            |..|:..:|..|.:...:..||..:         .|....|
plant   185 GRKYGGETDFKK------------LTDRLSELLGTFSIGSFVPWLAWVDWIRGWDAQLDKMGKDL 237

  Fly   249 HQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERP---LSNLDIRE-E 309
            ..|.||::....:...|:|:.                 .:|.||:...::.|   :..:.|:. .
plant   238 DDFFEKVVQDHEDGDRRDGTD-----------------LIDALLRVKREKSPGFEIERVSIKAIT 285

  Fly   310 VDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVK 374
            :|.|: .|.||:.:.|.:....:..||::..:..||:|::. ..||. ||.:.:..:.|:...:|
plant   286 LDVFV-GGSDTSFTLLEWAMTELLRHPKSLNRLQEEVRTIC-KGKSR-VSEDDIQGMKYLKAVIK 347

  Fly   375 ETLRMYPSVPLLG-RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFS-EPNIFKPERFDVVTT 437
            |.||::|..|::. .:..||.::....|||||.:.::...:||....:. :...|||||....:.
plant   348 EALRLHPPFPMMAPHESTEDVKLRDYHIPAGTQVMMNAWAIGREVATWGPDAEEFKPERHLDTSV 412

  Fly   438 AEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAE 494
            ..:...:..:||.||.|.|....||::..:.::||::..::.....:|.|....:||
plant   413 DFRGQNFELLPFGAGRRICPAVSFAVVLNEVVLANLVHGFDWKLPEESKEDKTDVAE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	106/486 (22%)
CYP71A25	NP_680107.1	CYP71-like	60..481	CDD:410695	96/454 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910