DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	148/516 - (28%)
Similarity:	234/516 - (45%)	Gaps:	86/516 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AILASALFVGLLLYHLKFKRLIDLISY-----MPGPPVLPLVGHGHHFIGKPPHEMVKKIFEF-M 65
            |::..:.:|...|..:.||..: |.||     :.|.|..||||.            :||.|.. .
plant    13 AVVVVSWWVWRTLQWVWFKPKM-LESYLRRQGLAGTPYTPLVGD------------LKKNFSMRA 64

  Fly    66 ETYSKD----------------QVLK-------VWLGPELNVLMGNPKDVEVVLGTLRFNDKAGE 107
            |..||.                |:||       .|.|....:.:.:|:.:..||..:....||..
plant    65 EARSKPINLTDDITPRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVLNKVYDFQKAHT 129

  Fly   108 YKALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRL-KHGDS 171
            : .|...:..|:|...|.||.|.|:||.||||.:.:...|..|.:...:::  .:.|:| ...:|
plant   130 F-PLGRLIATGVLSYDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIV--CKWDKLVSDKES 191

  Fly   172 GFSLYDWINLCTM--DTICETAMGVS-INAQS--NADSEYVQ-AVKTISMVLHKRMFNILYRFDL 230
            ...:..|..|.:|  |.|..||.|.| :..|.  ...:|..| .::|:     ::.|...|
plant   192 SCEVDVWPGLVSMTADVISRTAFGSSCVEGQRIFELQAELAQLIIQTV-----RKAFIPGY---- 247

  Fly   231 TYMLTPLARAEK-KALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQS 294
            :|:.|...|..| ||..:  |...:.||.:|   :|...:.|:.|||          .|.|||:|
plant   248 SYLPTKGNRRMKAKAREI--QVILRGIVNKR---LRAREAGEAPNDD----------LLGILLES 297

  Fly   295 TVDE---RPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKST 356
            .:.:   ..:|..|:.||...|.|.|.:|||..|::....::.|.:.|.:..||::.|.| ||..
plant   298 NLGQTKGNGMSTEDLMEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFG-DKEP 361

  Fly   357 PVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELF 421
            ..  |.||||..:.:.:.|.||:||.:|.|.|.:.::.|:....:|.|..|.:..|.:.|..||:
plant   362 DA--EGLNQLKVMTMILYEVLRLYPPIPQLSRAIHKEMELGDLTLPGGVLINLPILLVQRDTELW 424

  Fly   422 -SEPNIFKPERF-DVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVD 480
             ::...|||:|| |.::.|.| |..::.||:.|.|.||||.||:||.|..:|.:|:.:..:
plant   425 GNDAGEFKPDRFKDGLSKATK-NQASFFPFAWGSRICIGQNFALLEAKMAMALILQRFSFE 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	140/483 (29%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	146/505 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960