DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP76C4

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_182079.1	Gene:	CYP76C4 / 819163	AraportID:	AT2G45550	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	483	Identity:	115/483 - (23%)
Similarity:	195/483 - (40%)	Gaps:	85/483 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PGPPVLPLVGHGHHFIGKPPHEM---VKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVL 96
            ||||.||::|:.|. :||.||..   :.||:        ..::.:..|...:|::.:|:....||
plant    40 PGPPRLPIIGNIHQ-VGKNPHSSFADLAKIY--------GPIMSLKFGCLNSVVITSPEAAREVL 95

  Fly    97 GT-------LRFNDKA---GEYKALEPWLKEGLLVSRGRKWHKRRKI------------ITPAFH 139
            .|       .:.||..   |..:....||...     ..:|...||:            .|.|..
plant    96 RTHDQILSGRKSNDSIRCFGHEEVSVIWLPPS-----SARWRMLRKLSVTLMFSPQRTEATKALR 155

  Fly   140 FKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADS 204
            .|.:.:.|....:.|         :|.:..|...:.|..:    ::.|......|.:.:..:..|
plant   156 MKKVQELVSFMNESS---------ERKEAVDISRASYTTV----LNIISNILFSVDLGSYDSKKS 207

  Fly   205 EYVQ-----AVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELI 264
            ...|     |::..........|..:...||        :..:||:..|.:...::.....:..|
plant   208 NEFQDTVIGAMEAAGKPDAANYFPFMGFLDL--------QGNRKAMRGLTERLFRVFRGFMDAKI 264

  Fly   265 REGS----SQESSNDDADVGAKRKMAFLD-ILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSA 324
            .|.|    |::.||.|          ||| :|:.:..||..|.|.||...:......|.||:||.
plant   265 AEKSLGNYSKDVSNRD----------FLDSLLILNEGDEAELDNNDIEHLLLDMFTAGTDTSSST 319

  Fly   325 LMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLL-GR 388
            |.:....:..:|:...|...|:..|:|  :::.|....::.|.|:...||||.|::|:.||| .|
plant   320 LEWAMAELLRNPKTMVKAQAEMDRVLG--QNSVVQESDISGLPYLQAVVKETFRLHPAAPLLVPR 382

  Fly   389 KVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGP 453
            |...|.|:.|.::|..|.:.::...:||...::..|:.|:||||.......|...|...||..|.
plant   383 KAESDVEVLGFMVPKDTQVLVNVWAIGRDPSVWENPSQFEPERFMGKDIDVKGRDYELTPFGGGR 447

  Fly   454 RNCIGQKFAMLEIKAIVANVLRHYEVDF 481
            |.|.|...|:..:..::|::|  |..|:
plant   448 RICPGLPLAVKTVSLMLASLL--YSFDW 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	115/483 (24%)
CYP76C4	NP_182079.1	p450	11..505	CDD:299894	115/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910