DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and CYP704A1

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_850427.2	Gene:	CYP704A1 / 819098	AraportID:	AT2G44890	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	127/498 - (25%)
Similarity:	230/498 - (46%)	Gaps:	68/498 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ILASALFVGLLLYHLKF---KRLIDLISYMP-GPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETY 68
            :|:.||::.:.::..|.   ||      |.| ...:..|..|.|            |::::....
plant    18 LLSFALYLTIRIFTGKSRNDKR------YTPVHATIFDLFFHSH------------KLYDYETEI 64

  Fly    69 SKDQVLKVWLGP-ELNVLMGNPKDVEVVLGTLRFNDKAGEYKA--LEPWLKEGLLVSRGRKWHKR 130
            ::.:....:|.| :..:...:|::||.:|.|...|...|....  |...|..|:....|.||.::
plant    65 ARTKPTFRFLSPGQSEIFTADPRNVEHILKTRFHNYSKGPVGTVNLADLLGHGIFAVDGEKWKQQ 129

  Fly   131 RKIITPAFHFKILDQF-VEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGV 194
            ||:::..|..::|..| ..||...:..|:..:.:..|. |.| |...|.:..||:|:|.:...||
plant   130 RKLVSFEFSTRVLRNFSYSVFRTSASKLVGFIAEFALS-GKS-FDFQDMLMKCTLDSIFKVGFGV 192

  Fly   195 S---INAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKII 256
            .   ::..|....|:::|....:.....|:.:..::......:...:|. ||::.::.:|...:|
plant   193 ELGCLDGFSKEGEEFMKAFDEGNGATSSRVTDPFWKLKCFLNIGSESRL-KKSIAIIDKFVYSLI 256

  Fly   257 VQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTT 321
            ..:|:||    |.:::::...|:.:|       .||:|..|...:::..:|:.:...|..|.|||
plant   257 TTKRKEL----SKEQNTSVREDILSK-------FLLESEKDPENMNDKYLRDIILNVMVAGKDTT 310

  Fly   322 SSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKST--------PVSYELLNQLHYVDLCVKETLR 378
            :::|.:|.|.:..:|..|:|..:|||.|..:.:.|        .|:.|.|.|:.|:...:.||:|
plant   311 AASLSWFLYMLCKNPLVQEKIVQEIRDVTSSHEKTTDVNGFIESVTEEALAQMQYLHAALSETMR 375

  Fly   379 MYPSVPLLGRKVLEDCEINGKLIP------AGTNIGISPLYLGRREELF-SEPNIFKPERF--DV 434
            :||.||...|     |..|..::|      .|.||......:||...:: .:...|||||:  |.
plant   376 LYPPVPEHMR-----CAENDDVLPDGHRVSKGDNIYYISYAMGRMTYIWGQDAEEFKPERWLKDG 435

  Fly   435 VTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHY 477
            |...|  :.:.:|.|.||||.|||:.||..::| ||:..|.|:
plant   436 VFQPE--SQFKFISFHAGPRICIGKDFAYRQMK-IVSMALLHF 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	120/468 (26%)
CYP704A1	NP_850427.2	CYP86A	69..501	CDD:410687	115/429 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100859
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820