DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d1 and BAS1

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	132/527 - (25%)
Similarity:	236/527 - (44%)	Gaps:	50/527 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LVIGAILASALFVGLLLYHLKFKRLIDLISY--MPGPPVLPLVGHGHHFIGKP----------PH 55
            ||:..||:..:..|:.|...:.:::.:..|.  :.|||....:|:....:|..          .|
plant    14 LVLSVILSLVIVKGMSLLWWRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFSH 78

  Fly    56 EMVKKIFEFMETYSK--DQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEG 118
            .::.::..|...:.|  .....||.||...:.:.:|..:..:.....|.:|...:..::....:|
plant    79 NILPRVLSFYHHWRKIYGATFLVWFGPTFRLTVADPDLIREIFSKSEFYEKNEAHPLVKQLEGDG 143

  Fly   119 LLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCT 183
            ||..:|.||...||||:|.||.:.|...|.|..|...|::........::|:....:|:|..:.|
plant   144 LLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEVDVYEWFQILT 208

  Fly   184 MDTICETAMGVSINAQSNADSEYVQAVKTISMVL----HKRMFNILYRFDLTYMLTPLARAEKKA 244
            .|.|..||.|     .|..|...|..::...|:|    .:::|...|||..|       |...|:
plant   209 EDVISRTAFG-----SSYEDGRAVFRLQAQQMLLCAEAFQKVFIPGYRFFPT-------RGNLKS 261

  Fly   245 LNV---LHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDI 306
            ..:   :.:...|:|.:||:..| :|..:|.....|       ...|.:::|:    :.::..||
plant   262 WKLDKEIRKSLLKLIERRRQNAI-DGEGEECKEPAA-------KDLLGLMIQA----KNVTVQDI 314

  Fly   307 REEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDL 371
            .||..:|.|.|..|||:.|.:....::.|||.|.|..:|:..|.|: :..|....:: :|..:.:
plant   315 VEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGS-RDVPTKDHVV-KLKTLSM 377

  Fly   372 CVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELF-SEPNIFKPERF-DV 434
            .:.|:||:||.:....|:...|.::.|..||.||.:.|..:.:...:.:: ::.|.|.|.|| |.
plant   378 ILNESLRLYPPIVATIRRAKSDVKLGGYKIPCGTELLIPIIAVHHDQAIWGNDVNEFNPARFADG 442

  Fly   435 VTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRT 499
            |..|.| :|..:|||..|.|.||||..|:|:.|..:|.:::.:...........|.::..|..:.
plant   443 VPRAAK-HPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTFHLAPTYQHAPTVLMLLYPQH 506

  Fly   500 KEPLMFK 506
            ..|:.|:
plant   507 GAPITFR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	125/493 (25%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	117/450 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960