Protein Alignment Cyp4d1 and cyp11a1.1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_694485.2
• Gene: cyp11a1.1 / 80374
• ZFINID: ZDB-GENE-010306-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 493
• Identity: 104/493 - (21%)
• Similarity: 197/493 - (39%)
• Gaps: 98/493 - (19%)

  Fly    77 WLGPELNVL----MGNPKDVEVVL-------GTLRFNDKAGEYKA-------------------- 110
            |....|:||    ||..::|..::       |.: :.:|.|.|.:
Zfish    48 WRNSLLSVLAFTKMGGLRNVHRIMVHNFKTFGPI-YREKVGIYDSVYIIKPEDGAILFKAEGHHP 111

  Fly   111 ----LEPWL--------KEGLLVSRGRKWHKRRKIITPAFHF-KILDQFVEVFEKGSRDLLRNME 162
                ::.|.        |.|:|:..|:.|...|.|:...... |:...||.:.|:..:|.:..:.
Zfish   112 NRINVDAWTAYRDYRNQKYGVLLKEGKAWKTDRMILNKELLLPKLQGTFVPLLEEVGQDFVARVN 176

  Fly   163 QDRLKHGDSGFSLYDWINLCTMDTI---CETAMGVSINAQ-----SNADSEYVQAVKTISMVLHK 219
            :...:.|..     .|....|.|..   .|:...|....:     .|.|.|:...:..:| |:.|
Zfish   177 KQIERSGQK-----QWTTDLTHDLFKFSLESVSAVLYGERLGLLLDNIDPEFQHFIDCVS-VMFK 235

  Fly   220 RMFNILYRFDLTYMLTP-LARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKR 283
            ....:||       |.| |.|:....:...|......|..:.:..|:....|...|.:   |..:
Zfish   236 TTSPMLY-------LPPGLLRSIGSNIWKNHVEAWDGIFNQADRYIQNIFKQWKENPE---GNGK 290

  Fly   284 KMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRS 348
            ....|.|||.    :..||..||:..|...|..|.|:.:..|::..|.:|..|:.|    :|:|:
Zfish   291 YPGVLAILLM----QDKLSIEDIKASVTELMAGGVDSVTFTLLWTLYELARQPDLQ----DELRA 347

  Fly   349 VVGNDKSTPVSY-----ELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIG 408
            .:   .:..:::     :::..:..:...:|||||::|....|.|.:.||..|....|||||.:.
Zfish   348 EI---SAARIAFKGDMVQMVKMIPLLKAALKETLRLHPVAMSLPRFITEDTVIQNYHIPAGTLVQ 409

  Fly   409 ISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANV 473
            :....:||..:.|.:|..:.|.|:    .:.|...:..:.|..|||.|:|::.|..|::..:.::
Zfish   410 LGVYAMGRDHQFFPKPEQYCPSRW----ISSKRQYFKSLGFGFGPRQCLGRRIAETEMQIFLIHM 470

  Fly   474 LRHYEVDFVGDSSEPPVLIA---ELILRTKEPLMFKVR 508
            |.::.::     .:..:.:.   ||:|..::|:|..::
Zfish   471 LENFRIE-----KQKQIEVRSKFELLLMPEKPIMLTIK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	103/487 (21%)
cyp11a1.1	NP_694485.2	cytochrome_P450	75..498	CDD:477761	95/459 (21%)