Protein Alignment Cyp4d1 and cyp17a2

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001099140.1
• Gene: cyp17a2 / 796487
• ZFINID: ZDB-GENE-100822-1
• Length: 495
• Species: Danio rerio
• Alignment Length: 537
• Identity: 119/537 - (22%)
• Similarity: 221/537 - (41%)
• Gaps: 134/537 - (24%)

  Fly    11 SALFVGLLLYHLKFKRLID-----LISYMPGPPVLPLVGHGHHFIGK-PPHEMVKKIFEFMETYS 69
            |||   |||..|..:||::     .:|: |..|.|||:|...|.... |||.:      |.:..|
Zfish    11 SAL---LLLLLLLVRRLLEGVGSSSVSF-PCLPRLPLLGSLLHLRSNLPPHLL------FTQLSS 65

  Fly    70 K-DQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKI 133
            : ..:..::.||.|.:::..       :|.:|                 .:|:.|||::..|.|:
Zfish    66 QYGPLFGLYAGPHLTLVVSE-------IGLVR-----------------EVLLQRGREFAGRPKM 106

  Fly   134 ITPAFHFKILDQFVEVFEKGSRD--------LLRNMEQDRLKHGDSGFSLYDWINLCTMDTICET 190
            :|           .::..:|.:|        |.:|  ..||.|  |.|:|:.           |.
Zfish   107 VT-----------TDLLTQGGKDIAFADYSPLWKN--HRRLVH--SSFTLFG-----------EG 145

  Fly   191 AMGVSINAQSNADS--EYVQAVK----TISMVLHKRMFNILYR--FDLTY--------------- 232
            :..:....|..|||  |.:||.:    .:|:||.:.:.|::.|  |..:|
Zfish   146 SNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSSSYQPSDPELQTVIQYND 210

  Fly   233 -MLTPLARAE-------------------KKALNVLHQFTEKIIVQRREELIREGSSQESSNDDA 277
             ::..:||..                   |:.:::..|...|.:::.::.| ..|..::.. |..
Zfish   211 GIVQTIARGGLVDIFPWLRIFPNKDLKRLKECVSIRDQLLYKKLLEHKKSL-TPGEPRDLL-DAL 273

  Fly   278 DVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKC 342
            .:|.:|.....|.:.:..|         :....:.| ..|.:|||:.|::....:..||:.|::.
Zfish   274 LIGQQRGSGGADDITEDHV---------LMTAAEAF-GAGVETTSTTLLWTIAFLLHHPQLQERV 328

  Fly   343 FEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKV-LEDCEINGKLIPAGTN 406
            ..|:...||.|:  |........|..:|..:.|.:|:.|..|:|...| ::|..:.|..:|.||.
Zfish   329 QAELDECVGVDR--PPCLSDRPHLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTR 391

  Fly   407 IGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVA 471
            :.::...:....:.:.:|..|.|||| :..:.:|....:::||.||||.|:|:..|.:|:...|:
Zfish   392 VLVNMWAIHHDPKHWDQPEQFNPERF-LEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVS 455

  Fly   472 NVLRHYEVDFVGDSSEP 488
            ..|:.:......::|.|
Zfish   456 RPLQRFSFSCPSEASLP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	97/468 (21%)
cyp17a2	NP_001099140.1	CYP17A1	67..489	CDD:410766	97/471 (21%)