Protein Alignment Cyp4d1 and cyp4v2.2

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 212/516 - (41%)
• Similarity: 307/516 - (59%)
• Gaps: 15/516 - (2%)

  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGP-PVLPLVGHGHHFIGKPPHEMVKKIFEF 64
            :::....:|.:.|.:.:|.....:.|...::..:||| |..||:|.. .|:.....:...:|.|:
 Frog    11 VWVAAAVVLLTLLALSILPALQDYVRKRRILKPIPGPGPNYPLIGDA-LFLKNNGGDFFLQICEY 74

  Fly    65 METYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHK 129
            .|:|....:||||:|....:::.:...||.||.:.:..|||..||.|.|||.:|||.|.|.||..
 Frog    75 TESYRLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWRS 139

  Fly   130 RRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGD-SGFSLYDWINLCTMDTICETAMG 193
            |||:|||.|||.||.:|:||..:.|:.|:..::    .|.| ..|..:..:.||.:|.|.|||||
 Frog   140 RRKMITPTFHFAILSEFLEVMNEQSKILVEKLQ----THVDGESFDCFMDVTLCALDIISETAMG 200

  Fly   194 VSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQ 258
            ..|.||||.|||||||:..:|.::.:|........|..|......:...|.|.:||.||:|.|::
 Frog   201 RKIQAQSNRDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYAHLRDGKEHDKNLKILHSFTDKAILE 265

  Fly   259 RREELIREGSSQESSNDDADVGA---KRKMAFLDILLQSTVDE-RPLSNLDIREEVDTFMFEGHD 319
            |.|||.:.| .|:..:.|:|..:   |::.||||:||.:|.|. ..:|.:|||||||||||||||
 Frog   266 RAEELKKMG-EQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHD 329

  Fly   320 TTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVP 384
            ||::||.:..:.:.:|||||::..:|:..|.|. ...||:.:.|.:|.|::..:||:||:|||||
 Frog   330 TTAAALNWSLFLLGSHPEAQRQVHKELDEVFGK-SDRPVTMDDLKKLRYLEAVIKESLRIYPSVP 393

  Fly   385 LLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPF 449
            |.||.|.|||.|.|..:|.|.|:.|.|..|.|..|.|.||..|:|||| ....|...||||||||
 Frog   394 LFGRTVTEDCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERF-FPENASGRNPYAYIPF 457

  Fly   450 SAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRER 510
            |||.||||||:||::|.|.:::::||:|.|: .....|...|:.|||||.::.:..|::.|
 Frog   458 SAGLRNCIGQRFALMEEKVVLSSILRNYWVE-ASQKREELCLLGELILRPQDGMWIKLKNR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	194/435 (45%)
cyp4v2.2	NP_001072667.1	CYP4V	70..512	CDD:410773	198/449 (44%)