Protein Alignment Cyp4d1 and Cyp4f18

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 510
• Identity: 172/510 - (33%)
• Similarity: 262/510 - (51%)
• Gaps: 64/510 - (12%)

  Fly     5 IGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYS 69
            :|.|.:|.  .|||......:...|...:..| |:.|::...|....||
Mouse    64 LGLIQSSE--EGLLYIQSLVRTFRDACCWWVG-PLHPVIRIFHPAFIKP---------------- 109

  Fly    70 KDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKII 134
                  |.|.|.|..    |||...             |:.|:|||.:|||:|.|.||.:.|:::
Mouse   110 ------VVLAPALVA----PKDTVF-------------YRFLKPWLGDGLLMSTGDKWSRHRRML 151

  Fly   135 TPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQ 199
            ||||||.||..:|:|| ..|.:::....|.....|.:..::::.|:|.|:|::.:.......|.|
Mouse   152 TPAFHFNILKPYVKVF-NDSTNIMHAKWQRLASKGSAYLNMFEHISLMTLDSLQKCVFSFDSNCQ 215

  Fly   200 SNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELI 264
            .. .|||:.|:..:|.::.:|...:|...||.|.||......:||..::|.||:.:|.:||..|:
Mouse   216 EK-PSEYITAILELSTLVARRHQRLLLHVDLFYYLTHDGMRFRKACRLVHDFTDAVIRERRRTLL 279

  Fly   265 REGSSQESSNDDADVGAKRK-MAFLDILLQSTVDE--RPLSNLDIREEVDTFMFEGHDTTSSALM 326
            .:|..     |.....||.| :.|:|:||.|. ||  :.||:.|||.|.|||||.|||||:|.|.
Mouse   280 DQGGV-----DVLKAKAKAKTLDFIDVLLLSK-DEHGKALSDEDIRAEADTFMFGGHDTTASGLS 338

  Fly   327 FFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVL 391
            :..||:|.|||.|::|.:|:|.::.:.:...:.::.|.||.::.:|:||:||::|.|..:.|...
Mouse   339 WILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCT 403

  Fly   392 EDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRN 455
            :|..: :|::||.|....||.........::.:|.::.|.||| ....:..:|.|:|||||||||
Mouse   404 QDIVLPDGRVIPKGVISRISIFGTHHNPAVWPDPEVYDPFRFD-ADNVKGRSPLAFIPFSAGPRN 467

  Fly   456 CIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEP---PVLIAELILRTKEPLMFKV 507
            ||||.|||.|:|..:|..|..:.|  :.|..||   |    |||||.:..|..||
Mouse   468 CIGQTFAMSEMKVALALTLLRFRV--LPDDKEPRRKP----ELILRAEGGLWLKV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	163/478 (34%)
Cyp4f18	NP_077764.2	p450	52..516	CDD:365848	170/508 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845237
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750