Protein Alignment Cyp4d1 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001038763.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 491
• Species: Danio rerio
• Alignment Length: 480
• Identity: 137/480 - (28%)
• Similarity: 224/480 - (46%)
• Gaps: 65/480 - (13%)

  Fly     9 LASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQV 73
            |.||:||..|.|.|...::.....::||||      ..:..:|..|  .:.::.: .|.:..| :
Zfish    13 LLSAVFVVFLAYCLYIHQVHQKYDHIPGPP------RDNFLLGHIP--TINRVTK-SERHMND-L 67

  Fly    74 LKVW---LGP--ELN------VLMGNPKDVEVVLGTLRFNDKAGEYKAL-----EPWLKEGLLVS 122
            |.:|   .||  .||      :.:..|:..:.::.:.::......||.|     :.:|..||:.:
Zfish    68 LLIWAEKYGPVYRLNSFHYVIINVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGKRFLGYGLVTA 132

  Fly   123 RGRK-WHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDT 186
            .... |:::|:|:.|||....|...:..|.:.|..|:..:|:..:....:  .::|.:|..|:|.
Zfish   133 TDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLEEMAINKTPA--VMHDLVNCVTLDI 195

  Fly   187 ICETAMGVSINAQSNADSEYVQAVKTI--SMVLHKRMFNILYRFDLTYMLTP---LARAEKKALN 246
            ||:.|.||.:|.....|:.:.||::..  .|||..|        |......|   .|..|.|...
Zfish   196 ICKVAFGVDLNLFKQTDNPFQQAIEQCLQGMVLDLR--------DPFCKFFPKNWKAIQETKGAT 252

  Fly   247 VLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVD 311
            ||.:.|.:..:|.|:..:..|  ::..||           .|..:|::..:|:..:..|..:.:|
Zfish   253 VLLRKTGEQWIQNRKTAVEIG--EDVPND-----------ILTQILKTAKEEKVNNTKDHEQMLD 304

  Fly   312 ---TFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCV 373
               ||...|.:||::.|.|....:..|||..|:...|:..|:|..:.  :|||.|.:..|:...:
Zfish   305 NFVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGTKRD--ISYEDLGKFTYLSQVL 367

  Fly   374 KETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTA 438
            |||||:||:.|...|.:.||..|||..||.|.::..|.....|.|:.|.:|..|.||||:|  .|
Zfish   368 KETLRLYPTAPGTNRWLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKFDPERFNV--NA 430

  Fly   439 EKLNP-YAYIPFSAGPRNCIGQKFA 462
            .|  | |.|.|||.|||:|:||.|:
Zfish   431 PK--PYYCYYPFSLGPRSCLGQVFS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	129/454 (28%)
cyp46a1.3	NP_001038763.1	p450	39..452	CDD:278495	128/451 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920