Protein Alignment Cyp4d1 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 541
• Identity: 139/541 - (25%)
• Similarity: 249/541 - (46%)
• Gaps: 85/541 - (15%)

  Fly     3 LVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEF-ME 66
            ||:  ::.:.||:..:..|..|.:|     .:|||...|.||....:        .|.:..| ||
Zfish    13 LVV--LVITLLFIYGVWPHRFFIKL-----GIPGPRPWPFVGTLLSY--------AKGLCNFDME 62

  Fly    67 TYSKDQVLKVW--LGPELNVLMGNPKDVEVVLGTL------RFNDKAGEYKALEPWLKEGLLVSR 123
            ...|  ..|||  ....|.:||  ..|:||:...|      .|.::......|.....:|:::.:
Zfish    63 CAKK--YGKVWGIYDGRLPILM--VADLEVIKVVLVKECYSNFINRRKRTTGLAGPFSDGIIMVK 123

  Fly   124 GRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTIC 188
            ..:|.:.|..::|.|....|.:...:....:...::||::   |..:....:.:.:...::|.|.
Zfish   124 DERWKRMRSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQK---KDPEQPVKIKEVVAPYSLDVIT 185

  Fly   189 ETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTY--MLTPLARA-----EKKALN 246
            .::..|.|::.:|.:..:|..||..   :...|||.|....|.:  :..||.:.     .|.|::
Zfish   186 SSSFSVDIDSINNPEDPFVINVKKF---IQFNMFNPLLLLILLFPSLAIPLKKMGVTLFSKSAMD 247

  Fly   247 VLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQ----------STVDERP- 300
            ..:...:||                  .||.:..::.::.||.::||          |...|:|
Zfish   248 FFYSVLKKI------------------KDDHNKESEGRVDFLKLMLQNQIPDDQIQDSDTSEQPA 294

  Fly   301 --LSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKS----TPVS 359
              |::.:|..:...|:..|::|||:.|.|..||:||:|:..:|..|||      ||:    ||::
Zfish   295 KGLTDHEILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEI------DKNFPLDTPIT 353

  Fly   360 YELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP 424
            |:.|.::.|:::.:.|::|:.|:.|.|.|...:...|||..||.||.:||....|....:::..|
Zfish   354 YDALMRMDYLEMAINESMRLLPTAPRLERSAKKTVVINGLTIPEGTLVGIPTYVLSHDPDIWESP 418

  Fly   425 NIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPP 489
            ..|:||||.....:|.|. ||:|||..|||||||.::|::.:|..|..:|:::.|:...::..|
Zfish   419 GEFRPERFSPENKSEFLQ-YAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIP- 481

  Fly   490 VLIAELILRTKEPLMFKVRER 510
             |...:..:.|.|:..|:..|
Zfish   482 -LEMNVTFQPKVPITLKLIPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	119/462 (26%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	120/467 (26%)