Protein Alignment Cyp4d1 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 507
• Identity: 180/507 - (35%)
• Similarity: 283/507 - (55%)
• Gaps: 34/507 - (6%)

  Fly     5 IGAILASALFVGLLL--YHL--KFKRLIDLISYMPGPPVLPLVGHGHHF--IGKPPHEMVKKIFE 63
            ||..:|....|.|||  |.|  :.:|....:...||||...|.||.:.|  .||.    :.::..
 Frog    21 IGQFVALLCVVLLLLKAYALYSRGRRFAAALVPFPGPPAHWLYGHVNQFRRDGKD----LDRLMV 81

  Fly    64 FMETYSKDQVLKVWLGPELNVL-MGNPKDVEVVLGTLRFNDKAGE-YKALEPWLKEGLLVSRGRK 126
            ::..|  .....:|:|.....| :.:|...:||.|  |.:.|... |..|.||:.:|||:..|..
 Frog    82 WVNKY--PNAFPLWIGKFFGTLIITDPDYAKVVFG--RSDPKTSTGYNFLVPWIGKGLLILSGNT 142

  Fly   127 WHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETA 191
            |.:.|::|||.||:.:|..:|.:....::.:|.  |.|...:.|....|:..::|.|:|:|.:.|
 Frog   143 WFQHRRLITPGFHYDVLKPYVSLISDSTKIMLD--ELDVYSNKDESVELFQHVSLMTLDSIMKCA 205

  Fly   192 MGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKII 256
            .....|.|::.|::|:|||..:|.:..:|:....|..:|.|.|:|.....:||..::|..|:|:|
 Frog   206 FSYHSNCQTDKDNDYIQAVYDLSWLTQQRIRTFPYHSNLIYFLSPHGFRFRKACRIVHLHTDKVI 270

  Fly   257 VQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE--RPLSNLDIREEVDTFMFEGHD 319
            .||::.|       ||..:...|..||.:.||||||.|. ||  :.||:.|:|.|||||||||||
 Frog   271 GQRKKLL-------ESKEELEKVQKKRHLDFLDILLCSK-DENGQGLSHEDLRAEVDTFMFEGHD 327

  Fly   320 TTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVP 384
            ||||.:.:..|.:|||||.|:||.|||...:|..::  :.::.||::.|..:|:||:||:||.||
 Frog   328 TTSSGISWILYCMATHPEHQQKCREEISEALGERQT--MEWDDLNRMPYTTMCIKESLRLYPPVP 390

  Fly   385 LLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIP 448
            .:.|::.:.... :|:.:|||..:.:....:.|...::.:|.||.|.||. ...:.|.:.:|::|
 Frog   391 SVSRELAKPITFHDGRSLPAGMLVSLQIYAIHRNPNVWKDPEIFDPLRFS-PENSSKRHSHAFVP 454

  Fly   449 FSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTK 500
            |:|||||||||.|||.|:|..||..|:.:|:.  .|.|:||:...:|:||:|
 Frog   455 FAAGPRNCIGQNFAMNEMKVAVALTLKRFELS--PDLSKPPLKQPQLVLRSK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	159/433 (37%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	160/448 (36%)