Protein Alignment Cyp4d1 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 131/556 - (23%)
• Similarity: 207/556 - (37%)
• Gaps: 127/556 - (22%)

  Fly     3 LVIGAILASALFVGLLL--------YHLKFKRLIDLISYMPGPPVLPLVG--------------- 44
            |:..|:...||.|.|||        |.|..|.........||...||..|
 Frog     6 LLTSALCTLALPVLLLLTAAKLWEVYCLSRKDASCRNPLPPGTMGLPFFGETLQMVLQRRKFLQV 70

  Fly    45 ----HGH----HFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRF 101
                :|.    |..|.|.          :.....:.|.::.||....|.:..|..|..:||.
 Frog    71 KRRKYGRIYKTHLFGSPT----------VRVTGAENVRQILLGEHKLVSVHWPASVRTILGA--- 122

  Fly   102 NDKAGEYKALEPWLKEGLLVSRGRKWHK-RRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDR 165
                            |.|.:.....|| .:|:|..||..:.|..:|.:.|:   :|.|::  :.
 Frog   123 ----------------GCLSNLHDSEHKYTKKVIMQAFSREALANYVPLMEE---ELRRSV--NL 166

  Fly   166 LKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDL 230
            ....||...:|..|............:|...........|.:       :...:.|...|:...:
 Frog   167 WLQSDSCVLVYPAIKRLMFRIAMRLLLGCDPQRLGREQEETL-------LEAFEEMTRNLFSLPI 224

  Fly   231 TYMLTPLARAEKKALNVLH-QFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQS 294
            ....:.|.|. .:|.|::| |..|.|    :|:|.||...|   ..||              ||.
 Frog   225 DVPFSGLYRG-LRARNIIHAQIEENI----KEKLQREPDGQ---CRDA--------------LQL 267

  Fly   295 TVDE-----RPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRS--VVGN 352
            .:|.     .|::...::|.....:|.||.||:||.......:|.|.:..:|..:|:.|  ::.|
 Frog   268 LIDHSRRTGEPVNLQALKESATELLFGGHGTTASAATSLTTFLALHKDVLEKVRKELESQGLLSN 332

  Fly   353 --DKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLG--RKVLEDCEINGKLIPAGTNIGISPLY 413
              ::...:|.|:|.||.|....:|||||:.|  |:.|  |..|:...:||..||.|.|:..|...
 Frog   333 KPEEKKELSIEVLQQLKYTSCVIKETLRLSP--PVAGGFRVALKTFVLNGYQIPKGWNVIYSIAD 395

  Fly   414 LGRREELFSEPNIFKPERFDVVTTAEKLNP-------YAYIPFSAGPRNCIGQKFAMLEIKAIVA 471
            .....|||.:.:.|.|:||        |.|       :.:|||..|.|.|:|::||.:.:|..:.
 Frog   396 THGEAELFPDKDEFNPDRF--------LTPLPGDSSRFGFIPFGGGVRCCVGKEFAKILLKVFIV 452

  Fly   472 NVLRHYEVDFVGDSSEPPVLIAELILRTKE-PLMFK 506
            .:.|:.:.:.:..|  |.:..:.:|..... |..||
 Frog   453 ELCRNCDWELLNGS--PAMKTSPIICPVDNLPAKFK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	109/451 (24%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	114/504 (23%)