Protein Alignment Cyp4d1 and Cyp4a1

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 167/520 - (32%)
• Similarity: 284/520 - (54%)
• Gaps: 42/520 - (8%)

  Fly     5 IGAILASALFVGLLL-------YHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIF 62
            |...|..|..:||||       ::|:.:.|:......|.||.       |.|.|....:..|::.
  Rat    15 ISGFLQVASVLGLLLLLVKAVQFYLQRQWLLKAFQQFPSPPF-------HWFFGHKQFQGDKELQ 72

  Fly    63 EFM---ETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKA-GEYKALEPWLKEGLLVSR 123
            :.|   |.:........| |.:..:::.:|..::|:||  |.:.|| |.|:.|.||:..|||:..
  Rat    73 QIMTCVENFPSAFPRWFW-GSKAYLIVYDPDYMKVILG--RSDPKANGVYRLLAPWIGYGLLLLN 134

  Fly   124 GRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTI- 187
            |:.|.:.|:::|||||:.||..:|:......|.:|...||  |...||...::..|:|.|:||:
  Rat   135 GQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQ--LAGQDSSIEIFQHISLMTLDTVM 197

  Fly   188 -CETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQF 251
             |..:...|:....|..| |:||:..::.:.|.|:.||.::.|..|..:.......:|..:.|..
  Rat   198 KCAFSHNGSVQVDGNYKS-YIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHLFNRACQLAHDH 261

  Fly   252 TEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE-RPLSNLDIREEVDTFMF 315
            |:.:|..|:::|...|..::       |..||::.||||||.:.::. ..||:.|:|.|||||||
  Rat   262 TDGVIKLRKDQLQNAGELEK-------VKKKRRLDFLDILLLARMENGDSLSDKDLRAEVDTFMF 319

  Fly   316 EGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMY 380
            ||||||:|.:.:.||.:|||||.|::|.||::||:|:..|  ::::.|:|:.|..:|:||.||:|
  Rat   320 EGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSS--ITWDHLDQIPYTTMCIKEALRLY 382

  Fly   381 PSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPY 444
            |.||.:.|::...... :|:.:|.|..:.:|...|....:::..|.:|.|.||   ......:.:
  Rat   383 PPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVWPNPEVFDPSRF---APDSPRHSH 444

  Fly   445 AYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRE 509
            :::|||.|.|||||::|||.|:|.|||..|..:|:  :.|.::.|:.:..|:|::|..:...:::
  Rat   445 SFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFEL--LPDPTKVPIPLPRLVLKSKNGIYLYLKK 507

  Fly   510  509
              Rat   508  507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	158/479 (33%)
Cyp4a1	NP_787031.1	p450	52..503	CDD:278495	158/477 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850