Protein Alignment Cyp4d1 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 518
• Identity: 124/518 - (23%)
• Similarity: 223/518 - (43%)
• Gaps: 117/518 - (22%)

  Fly    31 ISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVV 95
            |.:|||            .:|.||         |:.|:                   ||:|.|||
  Fly    88 IFFMPG------------IMGNPP---------FLSTH-------------------NPQDFEVV 112

  Fly    96 L---GTLRFNDKAGEYKAL---EPWLKE------GLLVSRGRKWHKRRKIITPA--------FHF 140
            .   |.  :.::.|.|..|   |.:.|:      |::.::|:.|...|.::.|.        .::
  Fly   113 FRNEGV--WPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNVRLYY 175

  Fly   141 KILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSE 205
            |.:.|..:.|   .:.:|...:.|.|:..|   ...|.||..|::::...|:...:....|::.|
  Fly   176 KKMSQVNQEF---VQRILELRDPDTLEAPD---DFIDTINRWTLESVSVVALDKQLGLLKNSNKE 234

  Fly   206 YVQAVKTISMVLHKRMFNILYRF-----DL-------TYMLTPLARAEKKALNVLHQFTEKIIVQ 258
             .:|:|         :|:.|..|     ||       .|:.||..:...:||:.:.:.|...:.:
  Fly   235 -SEALK---------LFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDE 289

  Fly   259 RREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSS 323
            ..|.|.:|..       :..|..:.:.:.|:.||:  ||.:..:.:    .:|..| .|.|||||
  Fly   290 AIERLDKEAK-------EGVVRPENEQSVLEKLLK--VDRKVATVM----AMDMLM-AGVDTTSS 340

  Fly   324 ALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGR 388
            ........:|.:||.|.:..||:..|:.| |::..:...:..:.|:..|:||:.|::|.:....|
  Fly   341 TFTALLLCLAKNPEKQARLREEVMKVLPN-KNSEFTEASMKNVPYLRACIKESQRLHPLIVGNAR 404

  Fly   389 KVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERF-------DVVTTAEKL---NP 443
            .:..|..::|..:||||.:.|.||....|:|.|.:.:.|.|||:       :....|.:|   ||
  Fly   405 VLARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNP 469

  Fly   444 YAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFK 506
            :.::||..|||.|:|::...:|::...|.::|::.|:|  :........:.||.....||.||
  Fly   470 FVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEF--NYPTENAFRSALINLPNIPLKFK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	112/472 (24%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	121/514 (24%)