Protein Alignment Cyp4d1 and Cyp12a5

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 123/492 - (25%)
• Similarity: 220/492 - (44%)
• Gaps: 75/492 - (15%)

  Fly    56 EMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLK---- 116
            ||::.|....:.|.....|...:|.:..|:..||||.|||..    |:....::.....|:
  Fly    73 EMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFR----NEGVWPFRPGSDILRYHRT 133

  Fly   117 ----------EGLLVSRGRKWHKRRKIITPA--------FHFKILDQFVEVFEKGSRDLLRNMEQ 163
                      :|::.|:|:.|...|.|:.|.        .:||.:.|..:.|.    :|::.:..
  Fly   134 VYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFV----ELIKEIRD 194

  Fly   164 DRLKHGDSGFSLYDWINLCTMDTICETAMG--VSINAQSNADSEYVQAVKTI-SMVLHK---RMF 222
            ...:.....|  .:.||..|::::...|:.  :.:..:|..:||..:..|.: ...||.   .|.
  Fly   195 ASTQEVPGNF--LETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMK 257

  Fly   223 NILYRFDLTYMLTPLARAEKKALNVLHQFTEKII---VQRREELIREGSSQESSNDDADVGAKRK 284
            ..|:|    |..|||.:...:.::.:.:.|.|.:   ::|.|:..:||.          |..:.:
  Fly   258 PSLWR----YFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGV----------VRPEHE 308

  Fly   285 MAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSV 349
            .:.|:.||:  ||::..:.:    .:|..| .|.|||||........:|.:||.|.:..||:..|
  Fly   309 QSVLEKLLK--VDKKVATVM----AMDMLM-AGVDTTSSTFTALLLCLAKNPEKQARLREEVMKV 366

  Fly   350 VGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYL 414
            :.| |.:..:...:..:.|:..|:||:.|:||.|....|.:..|..|:|..:||||.:.:.|:..
  Fly   367 LPN-KDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINS 430

  Fly   415 GRREELFSEPNIFKPERF--DVVTTAEKL--------NPYAYIPFSAGPRNCIGQKFAMLEIKAI 469
            ...||.|.:|..|.|||:  :...:|.|.        ||:.::||..|||.|:|::...:|::..
  Fly   431 LYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELG 495

  Fly   470 VANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFK 506
            .|.::|::.|:|  :.|......:.||.....||.||
  Fly   496 TARLIRNFNVEF--NHSTKNAFRSALINLPNIPLKFK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	116/471 (25%)
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	117/479 (24%)