DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d1 and Cyp313a3

DIOPT Version :9

Sequence 1:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	126/503 - (25%)
Similarity:	221/503 - (43%)	Gaps:	79/503 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LASALFVGLLLYHLKFKRLIDLISY-MPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQ 72
            |..|:.|...:|.|..:|.:.::.: :|||..||::|..               ||::.||.:..
  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIA---------------FEYLITYKRKM 55

  Fly    73 VLK------------VWLGPELNVLMGNPKDV-EVVLGTLRFNDKAGEYKALEPWLKEGLLVSRG 124
            .::            ||:||...|:..:||.. |:.|.....|..:...|.:.....:|||....
  Fly    56 SIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLEA 120

  Fly   125 RKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNME----QDRLKHGDSGFSLYDW-INLCTM 184
            .||..|||.:.|||...:|..|:.:|...::.|:..::    |...|..|   .:..| ..:.|.
  Fly   121 SKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRD---DIVRWSFRIATQ 182

  Fly   185 DTICETAMGVSINAQSNADS---EYVQAVKTISM-VL----HKRMFNILYRFDLTYMLTPLARAE 241
            .|:   ...|..:|....||   .|...:|.|.| ||    |.::|:.|..|:     |..|.|:
  Fly   183 TTV---GTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFE-----TQKALAK 239

  Fly   242 KKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVD---ERPLSN 303
            .....::....:|.::.:.|    .||..|.::                ::...::   ...:|.
  Fly   240 SNVNKMIGTIVDKKLMTKPE----SGSQPEITS----------------VINKAIELHRNGEMSR 284

  Fly   304 LDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHY 368
            .:::.|..:|:....:||...:......:|..||.|...::|::.:........|:|:.|.::.:
  Fly   285 EEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVF 349

  Fly   369 VDLCVKETLRMYPSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGR-REELFSEPNIFKPER 431
            ::..|.||||:.||||...|:.:.|..: :|.:||.|..|||......| |:...::|:.|.|:.
  Fly   350 LERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDH 414

  Fly   432 FDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEV 479
            | :.......:||||||||.|.|||||.|:.::..|..::.:||:.:|
  Fly   415 F-LPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	120/476 (25%)
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	120/476 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.860