Protein Alignment Cyp4d1 and cyp51

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001001730.2
• Gene: cyp51 / 414331
• ZFINID: ZDB-GENE-040625-2
• Length: 499
• Species: Danio rerio
• Alignment Length: 531
• Identity: 138/531 - (25%)
• Similarity: 226/531 - (42%)
• Gaps: 100/531 - (18%)

  Fly     8 ILASALFVGLLLYHLKFKRLI------DLISYMPG-PPVLPLVGHGHHFIGKPPHEMVKKIFE-F 64
            :|.:::|...|.|   |.:|:      :...|.|. |..||.:|....| |:.|.|.::|.:| :
Zfish    24 LLTASVFTLTLGY---FSKLLFTQHSSEHTKYPPHIPSSLPFLGQAVAF-GRSPIEFLEKAYEQY 84

  Fly    65 METYSKDQVLKVW---LGPELNVLMGNPK-------DVEVVLGTLRFNDKAGEYKALEPWLKEGL 119
            ....|...|.|.:   ||.:...||.|.|       ||...|.|..|. |...|....|...|
Zfish    85 GPVVSFTMVGKTFTYLLGSDAAALMFNSKNEDLNAEDVYARLTTPVFG-KGVAYDVPNPLFLE-- 146

  Fly   120 LVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSG-FSLYDWINLCT 183
                      ::|::....:.....|.||:.|:.::|..|       :.|:|| .:|:|.::...
Zfish   147 ----------QKKMLKTGLNIAQFKQHVEIIEEETKDYFR-------RWGESGERNLFDALSELI 194

  Fly   184 MDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFD-----LTYML-----TPLA 238
            :.|......|..|.:                 :|.:|:..:....|     ..::|     .|..
Zfish   195 ILTASRCLHGCEIRS-----------------LLDERVAQLYADLDGGFTHAAWLLPGWLPLPSF 242

  Fly   239 RAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTV-DERPLS 302
            |...:|...:.:....:|.:|||:        ...:||          .|..|:.:|. |.||||
Zfish   243 RRRDRAHLEIKKIFYNVIKKRRED--------TEKHDD----------ILQTLIDATYKDGRPLS 289

  Fly   303 NLDIREEVDTFMFEGHDT--TSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQ 365
            :.:|...:...:..|..|  |:||.|.||  :|.....|::|:.|.:||.| ::..|:.|:.|..
Zfish   290 DDEIAGMLIGLLLAGQHTSSTTSAWMGFF--LARDRALQERCYSEQKSVCG-EELPPLHYDQLKD 351

  Fly   366 LHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPE 430
            |..:|.|:|||||:.|.:..:.|......::....||.|..:.:||....|.::.::|...|.|:
Zfish   352 LSLLDRCLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQVCVSPTVNHRLQDTWAERLDFDPD 416

  Fly   431 RF--DVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIA 493
            |:  |.....||   :|||||.||...|||:.||.::||.|.:.:||.::.:.| |...|||...
Zfish   417 RYLHDNPAAGEK---FAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDFELV-DGHFPPVNYT 477

  Fly   494 ELILRTKEPLM 504
            .:|.....|::
Zfish   478 TMIHTPHNPII 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	119/456 (26%)
cyp51	NP_001001730.2	CYP51-like	80..491	CDD:410668	121/471 (26%)