Protein Alignment Cyp4d1 and Cyp12c1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 137/535 - (25%)
• Similarity: 223/535 - (41%)
• Gaps: 110/535 - (20%)

  Fly    34 MPGPPVLPLV-----GHGHHFIGKPPHEMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVE 93
            :|||....|.     |..:|.:|         :.:.|..|.| |...:.|.|.   |.|.|..|
  Fly    44 LPGPTRWQLFRGFQKGGEYHQLG---------MDDVMRLYKK-QFGDICLIPG---LFGMPSTV- 94

  Fly    94 VVLGTLRFNDKAGE--YKALEPWLKEG---------------------LLVSRGRKWHKRRKIIT 135
                 ..||.:..|  |:....|...|                     .|...|.:|.|.|..:.
  Fly    95 -----FTFNVETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGNGAEWGKNRSAVN 154

  Fly   136 P--------AFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAM 192
            |        |.:.|.:.:....|....|: :|:.|...:. ||    ..:.||..|.:::...|:
  Fly   155 PVLMQHRNVAIYLKPMQRVNRQFVNRIRE-IRDKESQEVP-GD----FMNTINHLTFESVATVAL 213

  Fly   193 G--VSINAQSNADSEYVQAVKTISMVLHKRMFNI-----LYRFDLTYMLTPLARAEKKALNVLHQ 250
            .  :.:..::|...|..:..|.|. ||....|::     |||    |:.||..:...:|::.:..
  Fly   214 DRELGLLREANPPPEASKLFKNIE-VLMDSFFDLGVRPSLYR----YIPTPTYKKFSRAMDEIFD 273

  Fly   251 FTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMF 315
            .....:.|..|.:.|: |||..|||...|        |:.|||  :|.:    |.:...:|..|
  Fly   274 TCSMYVNQAIERIDRK-SSQGDSNDHKSV--------LEQLLQ--IDRK----LAVVMAMDMLM- 322

  Fly   316 EGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYEL----LNQLHYVDLCVKET 376
            .|.||||:|:.....|:|.:||.|::..||:.|     |.|.:..|.    :..|.|:...:||:
  Fly   323 GGVDTTSTAISGILLNLAKNPEKQQRLREEVLS-----KLTSLHSEFTVEDMKSLPYLRAVIKES 382

  Fly   377 LRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERF--------- 432
            ||:||......|....|..::|..||.||.:.::..:|.:.:.|:.....|.|||:
  Fly   383 LRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKS 447

  Fly   433 DVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELIL 497
            ||:...: ||.:.|:||..|||.|:|::...||::..|||::|::.::: ..|:|.|.. ...:.
  Fly   448 DVLMNKD-LNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEY-NYSTEKPYK-CRFLY 509

  Fly   498 RTKEPLMFKVRERVY 512
            :...||.||..:..|
  Fly   510 KPNIPLKFKFTDLKY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	122/481 (25%)
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	124/484 (26%)