Protein Alignment Cyp4d1 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 417
• Identity: 122/417 - (29%)
• Similarity: 201/417 - (48%)
• Gaps: 52/417 - (12%)

  Fly    89 PKDVEVVLGTLRFNDKAGEYKAL-----EPWLKEGLLVSRGRK-WHKRRKIITPAFHFKILDQFV 147
            |:..:.:|.:.::......|:.|     :.:|..||:.:.... |:::|:|:.|||....|...:
Zfish    38 PEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLRSLI 102

  Fly   148 EVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKT 212
            ..|::.|..|:..:|:  :.:..:...::|.:|..|:|.||:.|.||.:|..:..||.:..||:.
Zfish   103 STFDEMSERLMDKLEE--MANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQNAVEL 165

  Fly   213 I--SMVLHKRMFNILYRFDLTYMLTP----LARAEKKALNVLHQFTEKIIVQRREELIREGSSQE 271
            .  .|.:..|        |..:.|.|    |.:..:.|..:|.:..||.| |.|:..::.|.
Zfish   166 CLNGMTVDLR--------DPFFRLFPKNWKLIKQIRDAAELLRKTGEKWI-QNRKTAVKNGE--- 218

  Fly   272 SSNDDADVGAKRKMAFLDILLQ--STVDERPLSNLDIREEV----DTFMFEGHDTTSSALMFFFY 330
                  ||..       |||.|  .:.:|..::|.|..|::    .||...|.:||::.|.|...
Zfish   219 ------DVPK-------DILTQILKSAEEENVNNTDDLEQMLDNFVTFFIAGQETTANQLSFAIM 270

  Fly   331 NIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCE 395
            .:..:||..|:...|:..|:|..:.  :|.|.|.:..|:...:|||||:||:.|...|.:.||..
Zfish   271 ALGRNPEIYKRAKAEVDEVLGTKRE--ISNEDLGKFTYLSQVLKETLRLYPTAPGTNRWLHEDMI 333

  Fly   396 INGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNP-YAYIPFSAGPRNCIGQ 459
            |:|..||.|.::..|.....|.|:.|.:|..|.||||||  .|.|  | |.|.||:.|||.|:||
Zfish   334 IDGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPERFDV--NAPK--PYYCYFPFALGPRTCLGQ 394

  Fly   460 KFAMLEIKAIVANVLRHYEVDFVGDSS 486
            .|:.:|.|.::|.:|:.:|...|...|
Zfish   395 VFSQMEAKVVLAKLLQRFEFSLVPGQS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	122/417 (29%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	122/417 (29%)