Protein Alignment Cyp4d1 and cyp46a1.4

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_005160404.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 501
• Species: Danio rerio
• Alignment Length: 510
• Identity: 138/510 - (27%)
• Similarity: 232/510 - (45%)
• Gaps: 76/510 - (14%)

  Fly     9 LASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSKDQV 73
            |.||:|...|.|.|....:.....::||||      ..:...|..| .:.|.:      |:.|.:
Zfish    13 LLSAVFTAFLAYCLYIHYVHQKYDHIPGPP------RDNFLFGHSP-SLTKSM------YADDSL 64

  Fly    74 LK----VW---LGP--ELN------VLMGNPKDVEVVLGTLRFNDKAGEYKAL-----EPWLKEG 118
            :.    .|   .||  .:|      :::..|:..:.:|.:.::......|:.|     :.:|..|
Zfish    65 IHDLFLQWAEKYGPVYRINSLHYIAIVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYG 129

  Fly   119 LLVSRGRK-WHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLC 182
            |:.:.... |:::|:|:.|||....|...:..|::.|..|:..:|:  :.:..:...::|.:|..
Zfish   130 LITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEE--MANNKTPAVMHDLVNCV 192

  Fly   183 TMDTICETAMGVSINAQSNADSEYVQAVKTI--SMVLHKRMFNILYRFDLTYMLTPLARAEKKAL 245
            |:|.||:.|.||.:|..:..||.:..||:..  .|.:..|              .|..|...|..
Zfish   193 TLDVICKVAFGVDLNFLAQKDSPFQNAVELCLNGMTVDLR--------------DPFFRLFPKNW 243

  Fly   246 NVLHQFTEKIIVQRR--EELIREGSSQESSNDDADVGAKRKMAFLDILLQ--STVDERPLSNLDI 306
            .::||..:...:.|:  |:.|:...:...:.:|..         .|||.|  .:.:|..::|.|.
Zfish   244 KLIHQIRDAAELLRKTGEKWIQNRKTAVKNGEDVP---------KDILTQILKSAEEENVNNTDD 299

  Fly   307 REEV----DTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLH 367
            .|::    .||...|.:||::.|.|....:..:||..|:...|:..|:|..:.  :|.|.|.:..
Zfish   300 LEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKRE--ISNEDLGKFT 362

  Fly   368 YVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERF 432
            |:...:|||||:||:.|...|.:.||..|||..||.|.::..|.....|.|:.|.:|..|.||||
Zfish   363 YLSQVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPERF 427

  Fly   433 DVVTTAEKLNP-YAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSS 486
            ||  .|.|  | |.|.||:.|||.|:||.|:.:|.|.::|.:|:.:|...|...|
Zfish   428 DV--NAPK--PYYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFEFSLVPGQS 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	131/484 (27%)
cyp46a1.4	XP_005160404.1	p450	39..495	CDD:278495	131/484 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910