Protein Alignment Cyp4d1 and Cyp6a8

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 137/570 - (24%)
• Similarity: 233/570 - (40%)
• Gaps: 136/570 - (23%)

  Fly     1 MFLVIGAILASALFVGLLLYHLK-----FKRLIDLISYMPGPPVLPLVGHGHHFIGKPPH----- 55
            :|.|..|:||      :|.|::.     |||                  .|..|:.  ||
  Fly     7 LFQVAVALLA------ILTYYIHRKLTYFKR------------------RGIPFVA--PHLIRGN 45

  Fly    56 ----EMVKKIFE-FMETYSKDQVLKV-------WLGPELNVLMGNPKDVEVVLGTL-----RFND 103
                :..|.|.| |.:.|:|.:..|.       :..|...|:     |:|:....|     .|::
  Fly    46 MEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVI-----DLELAKQILIKDFSNFSN 105

  Fly   104 KAGEYKALEPWLKEGLLVSRGRKWHKRRKIITPAFH-----------FKILDQFVEVF-EKGSRD 156
            |...|...:..:...|....|.:|...|..::..|.           ..:.::|:.|. ||..:
  Fly   106 KGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK- 169

  Fly   157 LLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRM 221
                         :|...:.|.:...|:|.|...|.|:..|:..:..:|::...|  ..::.||.
  Fly   170 -------------NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGK--RSLVDKRH 219

  Fly   222 FNILYRFDLTYMLTPLARAEKKALNVLH--QF-----TEKIIVQRREELIREGSSQESSNDDADV 279
            ..:|..|..:|  ..|||.........|  :|     ||.:.|:.:|.:.|        ||
  Fly   220 GTLLNGFMRSY--PKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKR--------ND---- 270

  Fly   280 GAKRKMAFLDILLQ-STVDERPLSNLDI-----REEV--DTFMF--EGHDTTSSALMFFFYNIAT 334
                   |:|:|:: ....|..|.|.|:     .|||  ..|:|  .|.:|:||.:.|..|.:|.
  Fly   271 -------FMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAK 328

  Fly   335 HPEAQKKCFEEIRSVV-GNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEING 398
            :|:.|.|...|:..|: .:|::  .:||....|.|::..:.||||:|..||.|.|...:...:.|
  Fly   329 NPDIQDKVRAEVEEVIEQHDQN--FTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPG 391

  Fly   399 K---LIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQK 460
            .   :|.||.::.|....:.....::.||..|:||||....:|.:.: .|::||..|||||||.:
  Fly   392 HPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPS-VAWLPFGDGPRNCIGLR 455

  Fly   461 FAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAE---LILRTKEPLMFKV 507
            |..::.:..:|.::|:::  |...|..|..|:.:   .:|..|:.:..||
  Fly   456 FGQMQARIGLALLIRNFK--FSTCSKTPNPLVYDPKSFVLGVKDGIYLKV 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	115/478 (24%)
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	115/476 (24%)