Protein Alignment Cyp4d1 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_006240610.1
• Gene: Cyp46a1 / 362782
• RGDID: 1306605
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 140/534 - (26%)
• Similarity: 246/534 - (46%)
• Gaps: 82/534 - (15%)

  Fly     8 ILASALFVGLLLYHLKFKRLIDLISYMPGPPVLP--LVGHGHHFIGKPPHEMVKKIFE--FMETY 68
            :|.||:.:...|......|......::|||| .|  |:||..:|..|  .|...::.:  |::..
  Rat     7 LLGSAVLLAFGLCCTFVHRARSRYEHIPGPP-RPSFLLGHLPYFWKK--DEACGRVLQDVFLDWA 68

  Fly    69 SK-DQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGL----LVSR---GR 125
            .| ..|::|.:..:.:|::.:|:.|:..|.:.::|..:..|:|::....|.|    |||.   ||
  Rat    69 KKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRAIQTVFGERLFGQGLVSECDYGR 133

  Fly   126 KWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICET 190
             |:|:|:::..||....|...:..|.:.:..|:..:|..  ..|.:..|:.|.:...|:|.:.:.
  Rat   134 -WYKQRRVMDLAFSRSSLVSLMGTFNEKAEQLMEILEAK--ADGQTPVSMQDMLTCATIDILAKA 195

  Fly   191 AMGVSINAQSNADSEYVQAVKT-ISMVLHKRMFNILYRFDLTYMLTPLARAE----KKALNVLHQ 250
            |.|:..:....|.....||||. :..:...|  |.|.:|      .|..|.:    ::::.:|.|
  Rat   196 AFGMETSMLLGAQKPLSQAVKVMLEGISASR--NTLAKF------MPGKRKQLREIRESIRLLRQ 252

  Fly   251 FTEKIIVQRREELIREG------------SSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSN 303
             ..|..||||.|.::.|            .::|.:.||            ::||.:.|
  Rat   253 -VGKDWVQRRREALKRGEDVPADILTQILKAEEGAQDD------------EVLLDNFV------- 297

  Fly   304 LDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHY 368
                    ||...||:|:::.|.|....::..||...:...|:..|||:.:.  :.||.|.:|.|
  Rat   298 --------TFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRH--LDYEDLGRLQY 352

  Fly   369 VDLCVKETLRMYPSVPLLG--RKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPER 431
            :...:||:||:||  |..|  |.:.|:..|:|..:|..|.:..|...:||.:..|.:|..|.|:|
  Rat   353 LSQVLKESLRLYP--PAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDR 415

  Fly   432 FDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELI 496
            |.......:   :.|.|||.|.|:||||:||.:|:|.::|.:|:..|...|  ..:...|..:..
  Rat   416 FGPGAPKPR---FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV--PGQRFGLQEQAT 475

  Fly   497 LRTKEPLMFKVRER 510
            |:..:|::..:|.|
  Rat   476 LKPLDPVLCTLRPR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	133/502 (26%)
Cyp46a1	XP_006240610.1	p450	34..466	CDD:278495	130/482 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910