Protein Alignment Cyp4d1 and Cyp4e2

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 209/538 - (38%)
• Similarity: 310/538 - (57%)
• Gaps: 41/538 - (7%)

  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFM 65
            |:.|:...||..|.:...|....|:|. .:::...||..|||:|:.|. :||.|.|::..:|.:.
  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRR-RVLNKFNGPRGLPLMGNAHQ-MGKNPSEILDTVFSWW 63

  Fly    66 ETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKR 130
            ..|.||..: .|:|...|||:.:.|.:|.:|.:.....|:..|:...|||..|||.|.|.||||.
  Fly    64 HQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKH 127

  Fly   131 RKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVS 195
            ||:|||||||.||..|.||..:.|...:::::  .:..||:.|...:..:..|:|.||:||||||
  Fly   128 RKMITPAFHFNILQDFHEVMNENSTKFIKHLK--TVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190

  Fly   196 INAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQRR 260
            |||..|..|..|||.|.:...::.|.|:.|.|.:|.|.|.|...|..:.|..|..||.:||.:|
  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKR- 254

  Fly   261 EELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSAL 325
               |....|...|.:..|...::||||||.||.||:|.|||::.::.|||.||||||||||:|.:
  Fly   255 ---IEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGV 316

  Fly   326 MFFFYNIATHPEAQKKCFEEIRSVVGNDK-STPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRK 389
            .|..|.::.|.:.|:|.|:|.|.|:||.: ....:::.::|:.|:||.:||..|:|||||.:||.
  Fly   317 SFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRF 381

  Fly   390 VLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPR 454
            ..:|..|:|.|:|.||.:.:..:.||..|::|.:|:.|:||||::    ||..|:.|:|||||||
  Fly   382 TEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFEL----EKPGPFEYVPFSAGPR 442

  Fly   455 NCIGQKFAMLEIKAIVANVLRHYEV---------------------DFVGDSSEP------PVLI 492
            ||||||||:||||.:|:.::|::||                     |......:|      |:|.
  Fly   443 NCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILS 507

  Fly   493 AELILRTKEPLMFKVRER 510
            |.|.|:::..|..:::||
  Fly   508 AVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	183/458 (40%)
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	186/462 (40%)