Protein Alignment Cyp4d1 and Cyp4f39

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_796281.1
• Gene: Cyp4f39 / 320997
• MGIID: 2445210
• Length: 532
• Species: Mus musculus
• Alignment Length: 524
• Identity: 172/524 - (32%)
• Similarity: 288/524 - (54%)
• Gaps: 41/524 - (7%)

  Fly     4 VIGAILASALFVGLLLYHLKFKRLIDL------ISYMPGPPVLP-LVGHGHHFIGKPPHEM---- 57
            |:.|:|...||....|....||...|.      :|..|.||... |:||...::   |:|.
Mouse    23 VVSALLLLVLFFFFRLLVRAFKLFSDFRITCRKLSCFPEPPGRHWLLGHMSMYL---PNEKGLQN 84

  Fly    58 VKKIFEFMETYSKDQVLKVWLGPELNVL-MGNPKDVEVVLGTLRFNDKAGE--YKALEPWLKEGL 119
            .||:.:.|.     .::..|:||.|.:| :.:|..::.|||.........|  |..|:|||.:||
Mouse    85 EKKVLDTMH-----HIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGDGL 144

  Fly   120 LVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTM 184
            |:|:|.||.:.|:::||||||.||..::::|.:.:..:.....:...:...:.|.:::.|:|.|:
Mouse   145 LISKGNKWSRHRRLLTPAFHFDILKPYMKIFNQCTNIMHAKWRRHLAEGSVTSFDMFEHISLMTL 209

  Fly   185 DTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLH 249
            |::.:.....:.:.|... |:|:.::..:|.::.:|.:.:.:..|..|.||...|..::|.:.:|
Mouse   210 DSLQKCVFSYNSDCQERM-SDYISSIIELSALVVRRQYRLHHYLDFMYYLTADGRRFRQACDTVH 273

  Fly   250 QFTEKIIVQRREELIREGSSQESSNDDADVGAK--RKMAFLDILLQSTVDE-RPLSNLDIREEVD 311
            .||.::|.:||:.|.::|:       :|.:.||  :.:.|:|:||.:..:| :.||:.|||.|.|
Mouse   274 NFTTEVIQERRQALRQQGA-------EAWLKAKQGKTLDFIDVLLLAKDEEGKELSDEDIRAEAD 331

  Fly   312 TFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKET 376
            ||||||||||||.|.:..:|:|.:||.|:||.|||:.|:...:...:.::.|.||.:..:|:||:
Mouse   332 TFMFEGHDTTSSGLSWALFNLAKYPEYQEKCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKES 396

  Fly   377 LRMYPSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEK 440
            ||.:|.|.|:.|:..||.:: :|::||.|....:|.........::.:..::.|.||| ..|.::
Mouse   397 LRQFPPVTLISRRCTEDIKLPDGRVIPKGIICLVSIYGTHHNPIVWPDSKVYNPYRFD-PDTPQQ 460

  Fly   441 LNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHY--EVDFVGDSSEPPVLIAELILRTKEPL 503
            .:|.|::||||||||||||.|||.|::.:||..|..:  .||........|    ||||||:..|
Mouse   461 RSPLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRLSVDRTHKVRRKP----ELILRTENGL 521

  Fly   504 MFKV 507
            ...|
Mouse   522 WLNV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	149/439 (34%)
Cyp4f39	NP_796281.1	CYP4F	82..523	CDD:410772	153/458 (33%)