Protein Alignment Cyp4d1 and Cyp4a12a

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 525
• Identity: 163/525 - (31%)
• Similarity: 281/525 - (53%)
• Gaps: 63/525 - (12%)

  Fly     9 LASALFVGLLLY-----HLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETY 68
            :||.|.:.|||:     :|..:.|:......|.||...|.||              ||.
Mouse    21 VASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGH--------------KIL------ 65

  Fly    69 SKDQVLK--------------VWL-GPELNVLMGNPKDVEVVLGTLRFNDKA-GEYKALEPWLKE 117
             |||.|:              .|| |.::.:.:.:|..::::||  |.:.|| |.|:.|.||:..
Mouse    66 -KDQDLQDILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILG--RSDPKANGSYRFLAPWIGR 127

  Fly   118 GLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLC 182
            |||:..|:.|.:.|:::|||||:.||..:.|:.....|.:|...||  :...||...::..|.|.
Mouse   128 GLLMLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVRVMLDKWEQ--IVGQDSTLEIFRHITLM 190

  Fly   183 TMDTICETAMGVSINAQSNAD-SEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALN 246
            |:|||.:.|.....:.|.:.. ..|:|||:.::.::..|:.||.::.|:.|.::........|..
Mouse   191 TLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSNGCKANSACK 255

  Fly   247 VLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE-RPLSNLDIREEV 310
            :.|..|:::|..||.:|..|...::       :..||::.||||||.:.::. :.||:.|:|.||
Mouse   256 LAHDHTDQVIKSRRIQLQDEEELEK-------LKKKRRLDFLDILLFARMENGKSLSDKDLRAEV 313

  Fly   311 DTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKE 375
            |||||||||||:|.:.:.||.:||:||.|::|.:||:|::|:  .|.:::..|:::.|..:|:||
Mouse   314 DTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGD--GTSITWNDLDKMPYTTMCIKE 376

  Fly   376 TLRMYPSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAE 439
            .||:||.||.:.|::...... :|:.:|.|.::.:|...|.....::..|.:|.|.||   ....
Mouse   377 ALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRF---APGS 438

  Fly   440 KLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLM 504
            ..:.::::|||.|.|||||::|||.|:|..||..|..:|:  :.|.:..|:.|..::|::|..:.
Mouse   439 SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL--LPDPTRVPIPIPRIVLKSKNGIH 501

  Fly   505 FKVRE 509
            ..:::
Mouse   502 LHLKK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	144/449 (32%)
Cyp4a12a	NP_803125.2	CYP4B-like	70..503	CDD:410771	144/450 (32%)