Protein Alignment Cyp4d1 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 525
• Identity: 163/525 - (31%)
• Similarity: 281/525 - (53%)
• Gaps: 63/525 - (12%)

  Fly     9 LASALFVGLLLY-----HLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETY 68
            :||.|.:.|||:     :|..:.|:......|.||...|.||              ||.
Mouse    21 VASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGH--------------KIL------ 65

  Fly    69 SKDQVLK--------------VWL-GPELNVLMGNPKDVEVVLGTLRFNDKA-GEYKALEPWLKE 117
             |||.|:              .|| |.::.:.:.:|..::::||  |.:.|| |.|:.|.||:..
Mouse    66 -KDQDLQDILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILG--RSDPKANGSYRFLAPWIGR 127

  Fly   118 GLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLC 182
            |||:..|:.|.:.|:::|||||:.||..:.|:.....|.:|...||  :...||...::..|.|.
Mouse   128 GLLMLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVRVMLDKWEQ--IVGQDSTLEIFRHITLM 190

  Fly   183 TMDTICETAMGVSINAQSNAD-SEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALN 246
            |:|||.:.|.....:.|.:.. ..|:|||:.::.::..|:.||.::.|:.|.::........|..
Mouse   191 TLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSNGCKANSACK 255

  Fly   247 VLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDE-RPLSNLDIREEV 310
            :.|..|:::|..||.:|..|...::       :..||::.||||||.:.::. :.||:.|:|.||
Mouse   256 LAHDHTDQVIKSRRIQLQDEEELEK-------LKKKRRLDFLDILLFARMENGKSLSDKDLRAEV 313

  Fly   311 DTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKE 375
            |||||||||||:|.:.:.||.:||:||.|::|.:||:|::|:  .|.:::..|:::.|..:|:||
Mouse   314 DTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGD--GTSITWNDLDKMPYTTMCIKE 376

  Fly   376 TLRMYPSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAE 439
            .||:||.||.:.|::...... :|:.:|.|.::.:|...|.....::..|.:|.|.||   ....
Mouse   377 ALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRF---APGS 438

  Fly   440 KLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLM 504
            ..:.::::|||.|.|||||::|||.|:|..||..|..:|:  :.|.:..|:.|..::|::|..:.
Mouse   439 SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL--LPDPTRVPIPIPRIVLKSKNGIH 501

  Fly   505 FKVRE 509
            ..:::
Mouse   502 LHLKK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	155/490 (32%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	155/488 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845033
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750