Protein Alignment Cyp4d1 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 210/520 - (40%)
• Similarity: 303/520 - (58%)
• Gaps: 36/520 - (6%)

  Fly     4 VIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPV---LPLVGHGHHFIGKPPH-EMVKKIFEF 64
            |.||.:...:...|:.|..|::::      .|.|.|   .|||||.  ...||.: |..::|.::
  Rat    24 VAGATVLLNILQMLVSYARKWQQM------RPIPSVARAYPLVGHA--LFMKPNNTEFFQQIIQY 80

  Fly    65 METYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHK 129
            .|.:....::|:|:||...|.:...::|||:|.:.:..||:..||.|:|||..|||.|.|.||..
  Rat    81 TEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFMYKFLQPWLGLGLLTSTGSKWRA 145

  Fly   130 RRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKH-GDSGFSLYDWINLCTMDTICETAMG 193
            |||::||:|||.||:.|::|..:.:..|:..:|    || ....|:.:..|.||.:|.|||||||
  Rat   146 RRKMLTPSFHFTILEDFLDVMNEQANILVNKLE----KHVNQEAFNCFFPITLCALDIICETAMG 206

  Fly   194 VSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNVLHQFTEKIIVQ 258
            .:|.||||.|||||:.|..:|.::::||....:.|||.|::....|..||.|..||.||..:|.:
  Rat   207 KNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFKEGRDHKKGLKSLHTFTNNVIAE 271

  Fly   259 RREELIREGSSQESSNDDADVG-------AKRKMAFLDILLQSTVDE-RPLSNLDIREEVDTFMF 315
            |       .:::::..|....|       .||| ||||:||..|.:| ..||:.|||||||||||
  Rat   272 R-------VNARKAEQDCIGAGRGPLPSKTKRK-AFLDLLLSVTDEEGNKLSHEDIREEVDTFMF 328

  Fly   316 EGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMY 380
            ||||||::|:.:..|.:.::||.|:|..:|:..|.|. ...||:.|.|.:|.|:|..:|||||::
  Rat   329 EGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGR-SHRPVTLEDLKKLKYLDCVIKETLRVF 392

  Fly   381 PSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYA 445
            |||||..|.:.||||:.|..|..||...|.|..|.|....|.:|..|:|||| ....::..:|||
  Rat   393 PSVPLFARSLSEDCEVAGYKISKGTEAVIIPYALHRDPRYFPDPEEFQPERF-FPENSQGRHPYA 456

  Fly   446 YIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRER 510
            |:|||||||||||||||::|.|.|:|.:||.:.:: .....|...|..:||||....:..|::.|
  Rat   457 YVPFSAGPRNCIGQKFAVMEEKTILACILREFWIE-SNQKREELGLAGDLILRPNNGIWIKLKRR 520

  Fly   511  510
              Rat   521  520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	189/439 (43%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	191/453 (42%)