Protein Alignment Cyp4d1 and Cyp19a1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_058781.2
• Gene: Cyp19a1 / 25147
• RGDID: 2457
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 129/494 - (26%)
• Similarity: 213/494 - (43%)
• Gaps: 90/494 - (18%)

  Fly    13 LFVGLLLYHLKFKRLIDLISYMPGP----PVLPLVGHGHHF---IGKPPHEMVKKIFEFMETYSK 70
            |.:||||    ..|..:..|.:|||    .:.||:.||...   ||...:...|...|||
  Rat    30 LIMGLLL----LIRNCESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFM----- 85

  Fly    71 DQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALE--PWLKEGLLVSRGRK-WHKRRK 132
                :||:..|..:::.....:..|:....:..:.|..:.|:  ...:.|::.:.... |...|.
  Rat    86 ----RVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRP 146

  Fly   133 IITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGD----SGF----SLYDWINLCTMDTICE 189
            ....|.....|.:.|||..:..:..|     |||  ||    ||:    :|...|.|.|.:|:
  Rat   147 FFMKALTGPGLIRMVEVCVESIKQHL-----DRL--GDVTDNSGYVDVVTLMRHIMLDTSNTL-- 202

  Fly   190 TAMGVSINAQSNADSEYVQAVKTISMVLHKRMFN----ILYRFDLTYMLTPLARAEKKALNVLHQ 250
             .:|:.::..|        .||.|     :..||    :|.:.::.:.::.|.|..::::..|..
  Rat   203 -FLGIPLDESS--------IVKKI-----QGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKD 253

  Fly   251 FTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDER--PLSNLDIREEVDTF 313
            ..|.::.::|:::    ||.|...|..|...       |::..    ||  .|:..::.:.:...
  Rat   254 EIEILVEKKRQKV----SSAEKLEDCMDFAT-------DLIFA----ERRGDLTKENVNQCILEM 303

  Fly   314 MFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLR 378
            :....||.|..|......||.:||.:....:||.:||| |:...:..  :..|..|:..:.|:||
  Rat   304 LIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVG-DRDIRIGD--VQNLKVVENFINESLR 365

  Fly   379 MYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGR--REELFSEPNIFKPERFDVVTTAEKL 441
            ..|.|.|:.|:.|||..|:|..:..||||   .|.:||  |.|.|.:||.|..|.|      ||.
  Rat   366 YQPVVDLVMRRALEDDVIDGYPVKKGTNI---ILNIGRMHRLEYFPKPNEFTLENF------EKN 421

  Fly   442 NPYAYI-PFSAGPRNCIGQKFAMLEIKAIVANVLRHYEV 479
            .||.|. ||..|||:|.|:..||:.:|.::..:|:.:.|
  Rat   422 VPYRYFQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	109/427 (26%)
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	113/448 (25%)