Protein Alignment Cyp4d1 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 172/534 - (32%)
• Similarity: 271/534 - (50%)
• Gaps: 91/534 - (17%)

  Fly     1 MFLVIGAILASALFVGLLLYHLKFKR--LIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFE 63
            :.||:|.         |.|.||..:|  |...:...||||...|.||.               .|
Human    20 LILVLGF---------LKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHA---------------LE 60

  Fly    64 FMETYSKDQVLK----------VWLGPELNVL-------------MGNPKDVEVVLGTLRFNDKA 105
            ..||.|.|:|:.          :|.|..:..|             .|:||..:|
Human    61 IQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDV----------- 114

  Fly   106 GEYKALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGD 170
              |.....|:..||||..|.||.:.||::||.||:.:|..:|.||.:.:|.:|...| ::.:.|.
Human   115 --YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWE-EKAREGK 176

  Fly   171 SGFSLYDWINLCTMDTI--C-----ETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRF 228
            | |.::..:....::|:  |     :|.:|.|      .||.|..||..:::::.:|:.:..|..
Human   177 S-FDIFCDVGHMALNTLMKCTFGRGDTGLGHS------RDSSYYLAVSDLTLLMQQRLVSFQYHN 234

  Fly   229 DLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQ 293
            |..|.|||..|...:|..|.|..|:::|.:|:..|..|...::..|       :|.:.||||||.
Human   235 DFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQN-------RRHLDFLDILLG 292

  Fly   294 S-TVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTP 357
            : ..|:..||:.|:|.|||||||||||||:|.:.:|.|.:|.:||.|.:|.||:|.::|:...
Human   293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-- 355

  Fly   358 VSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCE-INGKLIPAGTNIGISPLYLGRREELF 421
            ..::.|.::.|:.:|:||:.|:||.||.:.|::.:... ::|:.:|||:.|.:....|.|...::
Human   356 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVW 420

  Fly   422 SEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSS 486
            .:|.:|...||. ...|.|.:|:|::||||||||||||:|||.|:|.:.|..|..:|  |..|.|
Human   421 PDPEVFDSLRFS-TENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE--FSLDPS 482

  Fly   487 EPPVLIAELILRTK 500
            ..|:.:.:|:||:|
Human   483 RLPIKMPQLVLRSK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	163/498 (33%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	163/498 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750