Protein Alignment Cyp4d1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 549
• Identity: 144/549 - (26%)
• Similarity: 253/549 - (46%)
• Gaps: 111/549 - (20%)

  Fly     8 ILASALFVGLLLY------HLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEF-M 65
            :||.:|   :|||      |..||:     ..:|||..||.:|...::        .|.:::| |
Mouse    14 LLAISL---VLLYRYGTRKHELFKK-----QGIPGPKPLPFLGTVLNY--------YKGLWKFDM 62

  Fly    66 ETYSKDQVLKVW------------LGPEL--NVLM-------GNPKDVEVVLGTLRFNDKAGEYK 109
            |.|.|  ..|.|            ..||.  |||:       .|.:|    .|.:....||
Mouse    63 ECYKK--YGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRD----FGPVGIMSKA---- 117

  Fly   110 ALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFS 174
                     :.:|:..:|.:.|.:::|.|....|.:...|.|:....|::.:.| :.|.| ...:
Mouse   118 ---------ISISKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQ-KAKKG-KPVT 171

  Fly   175 LYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFD------LTYM 233
            :.|.:...:||.|..|:.||::::.:|.:..:|:..|.            |.|||      .:.:
Mouse   172 MKDVLGAYSMDVITSTSFGVNVDSLNNPEDPFVEKAKK------------LLRFDFFDPLLFSVV 224

  Fly   234 LTPLARAEKKALNVLH------QFTEKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILL 292
            |.|......:.||:..      :|.:|.:.:.:|..:             |...|.::.||.:::
Mouse   225 LFPFLTPVYEMLNICMFPKDSIEFFKKFVDRMKESRL-------------DSKQKHRVDFLQLMM 276

  Fly   293 QS------TVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVG 351
            .|      .|..:.||:::|..:...|:|.|::||||.|.|..:::||||:.|||..:||...:.
Mouse   277 NSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALP 341

  Fly   352 NDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGR 416
            |  ..|.:|:.:.::.|:|:.:.||||:||....|.|...:|.|:||..||.|:.:.|....|..
Mouse   342 N--KAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHH 404

  Fly   417 REELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDF 481
            ..:.:|||..|:||||...... .::||.|:||..|||||:|.:||::.:|..:..:::::....
Mouse   405 DPQHWSEPEEFQPERFSKENKG-SIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQP 468

  Fly   482 VGDSSEPPVLIAELILRTKEPLMFKVRER 510
            ..::..|..|..:.:|:.::|::.||..|
Mouse   469 CKETQIPLKLSRQGLLQPEKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	120/469 (26%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	121/474 (26%)