Protein Alignment Cyp4d1 and Cyp19a1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_031836.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 492
• Identity: 122/492 - (24%)
• Similarity: 206/492 - (41%)
• Gaps: 86/492 - (17%)

  Fly    13 LFVGLLLYHLKFKRLI---DLISYMPGP----PVLPLVGHGHHF---IGKPPHEMVKKIFEFMET 67
            |.:||||       ||   :..|.:|||    .:.||:.||...   ||...:...|...|||
Mouse    30 LIMGLLL-------LIWNCESSSSIPGPGYCLGIGPLISHGRFLWMGIGSACNYYNKMYGEFM-- 85

  Fly    68 YSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALE--PWLKEGLLVSRGRK-WHK 129
                   :||:..|..:::.....:..|:....:..:.|..:.|:  ...:.|::.:.... |..
Mouse    86 -------RVWISGEETLIISKSSSMFHVMKHSHYISRFGSKRGLQCIGMHENGIIFNNNPSLWRT 143

  Fly   130 RRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINL---CTMDTICETA 191
            .|.....|.....|.:.|||..:..:..|     |||..........|.:.|   ..:||.....
Mouse   144 IRPFFMKALTGPGLVRMVEVCVESIKQHL-----DRLGEVTDTSGYVDVLTLMRHIMLDTSNMLF 203

  Fly   192 MGVSINAQSNADSEYVQAVKTISMVLHKRMFN----ILYRFDLTYMLTPLARAEKKALNVLHQFT 252
            :|:.::..:        .||.|     :..||    :|.:.::.:.::.|.|..::::..|....
Mouse   204 LGIPLDESA--------IVKKI-----QGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKDEI 255

  Fly   253 EKIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDER--PLSNLDIREEVDTFMF 315
            ..::.::|.::    |:.|...|..|...       |::..    ||  .|:..::.:.:...:.
Mouse   256 AVLVEKKRHKV----STAEKLEDCMDFAT-------DLIFA----ERRGDLTKENVNQCILEMLI 305

  Fly   316 EGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMY 380
            ...||.|..|.|....:|.:||.:....:||.:|||:   ..:..|.:..|..|:..:.|::|..
Mouse   306 AAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVGD---RDIKIEDIQNLKVVENFINESMRYQ 367

  Fly   381 PSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGR--REELFSEPNIFKPERFDVVTTAEKLNP 443
            |.|.|:.|:.|||..|:|..:..||||   .|.:||  |.|.|.:||.|..|.|      ||..|
Mouse   368 PVVDLVMRRALEDDVIDGYPVKKGTNI---ILNIGRMHRLEYFPKPNEFTLENF------EKNVP 423

  Fly   444 YAYI-PFSAGPRNCIGQKFAMLEIKAIVANVLRHYEV 479
            |.|. ||..|||.|.|:..||:.:|.::..:||.::|
Mouse   424 YRYFQPFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQV 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	101/422 (24%)
Cyp19a1	NP_031836.1	CYP19A1	72..485	CDD:410709	105/443 (24%)