Protein Alignment Cyp4d1 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 124/613 - (20%)
• Similarity: 210/613 - (34%)
• Gaps: 195/613 - (31%)

  Fly     1 MFLV-------IGAILASALFVGLL------LYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGK 52
            |||:       ..|.|.|||.:.||      |:.|::....|..|.:|    ||....|..|.|:
 Frog     1 MFLLEISYTSFFEAALTSALSLVLLLAASHQLWSLRWHSTRDRGSSLP----LPKGSMGWPFFGE 61

  Fly    53 PPHEMVK-------------KIFE-------FMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLG 97
            ..|.:|:             .||:       .:.....:.:.|:.||....|....|:..:::||
 Frog    62 TLHWLVQGSSFHSSRREKYGNIFKTHLLGKPVIRVTGAENIRKILLGEHHLVSTQWPQSTQIILG 126

  Fly    98 TLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNME 162
            :...::..||..                  .::||:::.......|:.::....:..|..:|:.
 Frog   127 SNTLSNSIGELH------------------RQKRKMMSKVLSSAALESYLPRIHEAVRWEVRSW- 172

  Fly   163 QDRLKHGDSGFSLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYR 227
                ..|....|:.......|........:|:|:     .|:::.:..:|...::..     |:.
 Frog   173 ----CRGVGPVSMLSCAKALTFRIAARILLGLSL-----TDTQFQELTRTFEQLVEN-----LFC 223

  Fly   228 FDLTYMLTPLARAEKKALNVLHQFTEKIIVQRREELIREGSSQESSN--DDADVGAKRKMAFLDI 290
            ..|....:.| |...||.:.|||:        .||.|:|..|:...:  :||          ||.
 Frog   224 LPLDIPFSGL-RKGMKARDTLHQY--------MEEAIKEKLSKRDPDACEDA----------LDY 269

  Fly   291 LLQSTVD-ERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRS------ 348
            |:.|..: .:.::..:::|.....:|....||:||.......:..||.|..|..:|:.|
 Frog   270 LINSAKEGGKEINMQELKESAIELIFAAFLTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEH 334

  Fly   349 --------------------------------VVG------------------------------ 351
                                            |:|
 Frog   335 CEQCLPATENPNNNILQDNGHQCLTAGCQLPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSS 399

  Fly   352 ----------------NDKS--TPV-----------------SYELLNQLHYVDLCVKETLRMYP 381
                            :|||  :||                 |.|.|..|||:|..|||.||:.|
 Frog   400 KNLVNGENRIQEAPCSHDKSNCSPVPGKLQNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLP 464

  Fly   382 SVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAY 446
            .|....|..|:..|::|..||.|.::..|.........::....:|.||||.......||..:.|
 Frog   465 PVSGGYRTALQTFELDGYQIPKGWSVMYSIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNY 529

  Fly   447 IPFSAGPRNCIGQKFAMLEIKAIVANVL 474
            |||..|.|:|||::.|.:.:|.:...::
 Frog   530 IPFGGGARSCIGKELAQIILKILAMELV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	100/508 (20%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	105/551 (19%)