Protein Alignment Cyp4d1 and Cyp2c69

DIOPT Version :9

• Sequence 1: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001097995.1
• Gene: Cyp2c69 / 100043108
• MGIID: 3721049
• Length: 491
• Species: Mus musculus
• Alignment Length: 550
• Identity: 116/550 - (21%)
• Similarity: 210/550 - (38%)
• Gaps: 146/550 - (26%)

  Fly    14 FVGLLLYHLKFKRLIDL-------ISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMETYSK- 70
            ||.|:|. |.|..|:.|       .:..|||..||::|: :|.|.      :|.|.:.:..:||
Mouse     4 FVVLVLC-LSFMLLLSLWRQRSARRNLPPGPTPLPIIGN-YHLID------MKDIGQCLTNFSKT 60

  Fly    71 -DQVLKVWLGPELNVLMGNPKDVEVVL----------GTLRFNDKAGEYKALEPWLKEGLLVSRG 124
             ..|..::.|.:..|::...:.::..|          |:..|.||..:.|        |:..|.|
Mouse    61 YGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGK--------GIGFSHG 117

  Fly   125 RKWHKRRKIITP------AFHFKILDQFVEVFEKGSRDLLRNME--------------------- 162
            ..| |..::.|.      |...:.::..|   ::.::.|::.::
Mouse   118 NVW-KATRVFTVNTLRNLAMGKRTIENKV---QEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVI 178

  Fly   163 -----QDRLKHGDSGF-SLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVL---- 217
                 |:|..:.|..| ||...:|.||                ....|...|....:.:::
Mouse   179 CSIVFQNRFDYKDKDFLSLIGKVNECT----------------EILSSPGCQIFNAVPILIDYCP 227

  Fly   218 --HKRMFNILYRFDLTYMLTPLARAEKKALNVLH--QFTEKIIVQRREELIREGSSQESSNDDAD 278
              |.:.|. .:.:..:|:|..: :..:::|:|.:  .|.:..::|||:                |
Mouse   228 GRHNKFFK-NHTWIKSYLLEKI-KEHEESLDVTNPRDFIDYFLIQRRQ----------------D 274

  Fly   279 VGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCF 343
            .|.:.        ::.|::.  |:.|     |...:|.|.:|.||.:.|....:..|.....|..
Mouse   275 KGIEH--------MEYTIEH--LATL-----VTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQ 324

  Fly   344 EEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPL-LGRKVLEDCEINGKLIPAGTNI 407
            |||.:|:|..:| |...: ...:.|.:..|.|..|.....|. |..:|..|.:.....||.||.:
Mouse   325 EEIDNVIGRHRS-PCMQD-RKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQV 387

  Fly   408 GISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVAN 472
            ..|...:......|..|.:|.|..|.......|.:.| ::|||||.|.|:|:..|.:|:...:..
Mouse   388 MTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDY-FVPFSAGKRICVGESLARMELFLFLTT 451

  Fly   473 VLRHY---------EVD----FVGDSSEPP 489
            :|:::         ::|    :.|.|..||
Mouse   452 ILQNFKLKPLVDPKDIDTTPKYSGFSKIPP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	107/521 (21%)
Cyp2c69	NP_001097995.1	p450	30..487	CDD:278495	107/522 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010