Protein Alignment wapl and wapla

DIOPT Version :10

• Sequence 1: NP_525042.2
• Gene: wapl / 31187
• FlyBaseID: FBgn0004655
• Length: 1741
• Species: Drosophila melanogaster
• Sequence 2: XP_688605.6
• Gene: wapla / 553345
• ZFINID: ZDB-GENE-131010-1
• Length: 1153
• Species: Danio rerio
• Alignment Length: 1229
• Identity: 324/1229 - (26%)
• Similarity: 507/1229 - (41%)
• Gaps: 308/1229 - (25%)

  Fly   577 TTRSDHDFD----------------SQSSVLGSISSKGNSTPQLLAQAVQEDSCVIRSRGSSVIT 625
            |.:|:.|.|                |:.:::.|.||.|:|| .:...||..:|....|..||.:|
Zfish    90 TAQSEMDSDTAGPKNEQLKTQTEKPSRGTLVTSTSSLGSST-NISRGAVGVNSPAKTSPASSYVT 153

  Fly   626 SDLET------------SQHSSLVAPPSDIESRLESM-MMTIDGAGTGAASAVPETPLQEDILAV 677
            ..:.|            ||.|||..|...|.:..:|. ..:..|||.|:::   :|....|.|..
Zfish   154 GTVGTWSKSNVTVSKQLSQVSSLKTPSRGISNDWDSFGEDSPPGAGEGSST---QTSNSSDELKS 215

  Fly   678 LRGEVPRLNGNTDPEPTEEE--DQQQQP---------KRATRGRGRKANNNVDVTPPATETRTRG 731
            .. :.|     .:|||..|:  |.:|.|         .|..||:..:::...|..|..:......
Zfish   216 AE-QCP-----AEPEPPVEQPVDFEQLPLLKPSSDRVYRRPRGKETESSAAGDTIPAVSSVSAPA 274

  Fly   732 RAKGADATTA---AISPPTGKRNTRGTRGSRKAEQEVDMEVDETAMTTVPAN---EEQLEQATLP 790
            ....::|..|   .:.||.|:...|            |..|...:..:| .|   ::.:|:
Zfish   275 PVMSSNAGVAGSSGVKPPAGRGRVR------------DYTVLHPSCVSV-CNVTIQDSIER---- 322

  Fly   791 PRRGRNAAARANNNNLASVNNNINKIAANLSAKAEASRLAEGGVAGGAARSYGRKRKNQ------ 849
                             ||::.:..:.|::                |.|.::.||...|
Zfish   323 -----------------SVDDFVMPVQADI----------------GEAGTFRRKADTQAPKPTR 354

  Fly   850 -QVTQVLQQEPVP------EEQETPDAEEEQ----PTPAKIPHTDHREHSPDHDPDPDPDELSNN 903
             :.||...::...      ||.|..||:.:.    .|..||.:....:.|.....|.|.......
Zfish   355 FRPTQSKSKKETKLEFFGFEENEAQDADGDATGSGSTSYKIKYFGFDDLSESDSEDDDDSAARER 419

  Fly   904 SNNSSLQHDGSSS---SPPPRDFKFKDKFKRTLTLDTQGAAN-AGAGGAAAAAPPESSGEQRGAV 964
            ..|...:.:..|:   ||...|.:...:.:.:|:.|:|.:.: .||.|:......:.|.:
Zfish   420 KKNKKAEAEALSTGTGSPQFSDSQESQQSQSSLSTDSQESLDETGATGSQKERHRKQSNK----- 479

  Fly   965 KLVISKKKG-SIFKSRALVPSDQAEQATVAKRHLYKHSWDAALEANGGGTNSDASNA------SA 1022
                ||:.| .||..    |.....:|....||     |:   :.......:.||:.      ||
Zfish   480 ----SKEIGRKIFSG----PKKSPAKAVYNARH-----WN---QPESEEVPTPASHTVAVPKPSA 528

  Fly  1023 SGVGVAGAKDHLHHLAAGKSDGDFGDSPSSNNNGSSSACSSASTLRGDSPALGKISRLAGKQGVP 1087
            |....:.:||...|    |.||.|...|                     |....|..:.
Zfish   529 SSSSTSSSKDTNSH----KDDGVFKAPP---------------------PPPKVIKSVT------ 562

  Fly  1088 ATSTSSDAFDLDLEPIAGELDLERSAAGASAGGTGATTGGGGATGGGGPVRVDRKTKDYYPVVRN 1152
                           |..||:.:...|                      ::..::.|:.|.||::
Zfish   563 ---------------IPTELNQDIVTA----------------------LKCRKEHKELYTVVQH 590

  Fly  1153 VKTAHQIQEIGEYQEMDDDVEYILDALQPHNPPATRCLSALQLAAKCMMPAFRMHVRAHGVVTKF 1217
            ||..:.:.|.||.||..||.||:...|:...|..|||||.:.||.:|.||:||||:||.|.|.:.
Zfish   591 VKHFNDVVEFGENQEFTDDFEYLETGLKSTQPLNTRCLSIISLATRCAMPSFRMHLRARGKVAQV 655

  Fly  1218 FKALSDANKDLSLGLCTSAIMYILSQEGLNMDLDRDSLELMINLLEA---DGVGGSTETGHPDRA 1279
            ||.||||.:..::.|||:::|||||::.|||||||..|||||.|||.   |.|..........:.
Zfish   656 FKMLSDAQQHPNMALCTASLMYILSRDRLNMDLDRSCLELMIRLLEMEQDDSVADQLTAKEMSKV 720

  Fly  1280 GYDRNKQKVRELCEEIKAQGKGTHLNVDSLTVGTLAMETLLSLTSKRAGEWFKEDLRKLGGLEHI 1344
                 |:|:|:|||.:    ...||:::::|.|.|||||||||||||||:||||:||.||||:||
Zfish   721 -----KEKIRKLCETV----HNKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHI 776

  Fly  1345 IKTISDFCRPVIACDTEIDWQPTLLDNMQTVARCLRVLENVTQHNETNQRYMLTSGQGKAVETLC 1409
            :..:.: |  |...:.|.| :.:|:.::....|||||||:||.||..||.|::.....:.:.:..
Zfish   777 VDKVKE-C--VENLNKEED-KESLVASLWGAERCLRVLESVTVHNPENQAYLIAYKDSQLIMSSA 837

  Fly  1410 QLYRLCSRQIMLHPSDGGGSNK--------EHPGVAMRELLVPVLKVLINLTHTFNEAQPSLGAE 1466
            :..:.|.:.|..:..:...|:.        .:.|.|:.:.:..|:.||:||||. ||    .|:.
Zfish   838 RALQHCEQMIQRYSREVSSSSSSTLPQSSHSNVGKAVEDCMRAVIGVLLNLTHD-NE----WGST 897

  Fly  1467 LLGQRGDVVETSFRLLLLSANYIPDQCVFELSILVLTLLINLCMHTVPNRAALMQAAAPAEYVAD 1531
            ..|::..::.|:...:|....|:|.:..|::.:|.|.|||||..::..||..|::......|:.:
Zfish   898 KTGEQDGLILTALDCVLKVPRYLPQEQRFDIRVLGLGLLINLVEYSARNRECLVEMEVDMSYLME 962

  Fly  1532 --------------------------NPPAQGSVSALQALLEYFYKCEELARLVEKNTDAFL--- 1567
                                      ......|::||.||::.|.:.|..|.|.|..||..:
Zfish   963 AEAVVKMENDVKTEEQKRDQMEEEEKRKATLKSLNALAALVQLFLERERAAVLAEAQTDDLISEA 1027

  Fly  1568 -----------------------ESNEKGKKKQEEVEE-TVNNLVQRAGHHMEHTLKGSYAAILV 1608
                                   |:|:...||:||.|| .:|..:|.||.|||.::..||:|:|:
Zfish  1028 PKSQADQSGEWQETSGEIQWVASETNDTNDKKEEEEEELDLNKALQHAGKHMEDSIVASYSALLL 1092

  Fly  1609 GNLIADNELYESVVRRQLRGNSFKEIIGVLEKYHTFMNLTSSLEAAFVAHMKSTKRIID 1667
            |.|...:.:....||..|....|..:..:|:|:..|||||.|:.   ....||..|:||
Zfish  1093 GCLCQGSPMNVKTVRENLPKGDFSIMTEMLKKFLNFMNLTCSVG---TTGQKSISRVID 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wapl	NP_525042.2	PHA03307	69..>436	CDD:223039
		WAPL	1152..1515	CDD:462278	146/373 (39%)
wapla	XP_688605.6	None