DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgd and AT5G41670

DIOPT Version :9

Sequence 1:	NP_001259175.1	Gene:	Pgd / 31185	FlyBaseID:	FBgn0004654	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001318724.1	Gene:	AT5G41670 / 834169	AraportID:	AT5G41670	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	236/475 - (49%)
Similarity:	314/475 - (66%)	Gaps:	16/475 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFL---ANEAKDTKVIGADSLEDMVSKLKS 68
            |.|.|||||||||.||:.:|||.:..||||.:||.|.|   :||.| ..|.|..|..|.|..::.
plant     9 IGLAGLAVMGQNLALNIADKGFPISVYNRTTSKVDETLDRASNEGK-LPVAGQYSPRDFVLSIQR 72

  Fly    69 PRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGE 133
            ||.|::|||||:.||..|..|...:..||.||||||..||:|.||..|..|.|||::|.||||||
plant    73 PRSVIILVKAGAPVDQTISALSEYMEPGDCIIDGGNEWYQNTERRIVEAEKKGLLYLGMGVSGGE 137

  Fly   134 EGARHGPSLMPGGHEAAWPLIQPIFQAICAKADGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLI 198
            ||||:||||||||...|:..::.|.:.:.|:.:..||..::|:||:|:|||||||||||||||||
plant   138 EGARNGPSLMPGGSFTAYNNVKDILEKVAAQVEDGPCVTYIGEGGSGNFVKMVHNGIEYGDMQLI 202

  Fly   199 CEAYHIMQSL-GLSADQMADEFGKWNSAELDSFLIEITRDILKYKD--GKGYLLERIRDTAGQKG 260
            .|||.::::: |||.|::|:.|.:||..||:|||:|||.||.:.||  |.|.|:::|.|..|.||
plant   203 SEAYDVLKNVGGLSNDELAEIFTEWNRGELESFLVEITSDIFRVKDDYGDGELVDKILDKTGMKG 267

  Fly   261 TGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLKGPSTKAQVANLT------KFLD 319
            |||||...|.:..|....|..::..|.||.|||||..|:.||:....|..:.:.:      :.:|
plant   268 TGKWTVQQAAELSVAAPTIAASLDCRYLSGLKDERENAAKVLEEAGLKEDIGSASRGVDKKRLID 332

  Fly   320 DIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPEL 384
            |::.|||.:||.|||||..|:|..:.|..|.||.|.:|.:|:||||||:|||..||.||...|.|
plant   333 DVRQALYASKICSYAQGMNLLRAKSLEKGWDLNLGEMARIWKGGCIIRAVFLDRIKKAYQRNPNL 397

  Fly   385 SNLLLD-DFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYF 448
            ::|::| ||.|:.::| |.:||.||..|...||..|.:..:|:::|.||.|:|||||:|||||.|
plant   398 ASLVVDPDFAKEMVQR-QAAWRRVVGLAISAGISTPGMCASLAYFDTYRRARLPANLVQAQRDLF 461

  Fly   449 GAHTYELLGQEGQFHHTNWT 468
            ||||||...:.|.: ||.||
plant   462 GAHTYERTDRPGAY-HTEWT 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgd	NP_001259175.1	NAD_binding_2	4..176	CDD:281445	86/171 (50%)
		PRK09287	15..471	CDD:236453	230/467 (49%)
		6PGD	180..467	CDD:278805	145/296 (49%)
AT5G41670	NP_001318724.1	PLN02350	1..487	CDD:215200	236/475 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	289	1.000	Domainoid score	I367
eggNOG	1	0.900	-	-		E1_COG0362
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68268
Inparanoid	1	1.050	443	1.000	Inparanoid score	I403
OMA	1	1.010	-	-		QHG62610
OrthoDB	1	1.010	-	-		D847823at2759
OrthoFinder	1	1.000	-	-		FOG0002705
OrthoInspector	1	1.000	-	-		otm3130
orthoMCL	1	0.900	-	-		OOG6_100975
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1807
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740