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Protein Alignment Pgd and PGD

DIOPT Version :9

Sequence 1:	NP_001259175.1	Gene:	Pgd / 31185	FlyBaseID:	FBgn0004654	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_002622.2	Gene:	PGD / 5226	HGNCID:	8891	Length:	483	Species:	Homo sapiens

Alignment Length:	481	Identity:	346/481 - (71%)
Similarity:	403/481 - (83%)	Gaps:	3/481 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMVSKLKS 68
            ||||||||||||||||||||::.||||||:||||:||.:|||||||.|||:||.||::||||||.
Human     3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKK 67

  Fly    69 PRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGE 133
            ||:::||||||.||||||::|||||..||:|||||||||:||:|||.:|...|:|||||||||||
Human    68 PRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGE 132

  Fly   134 EGARHGPSLMPGGHEAAWPLIQPIFQAICAK-ADGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQL 197
            ||||:||||||||::.|||.|:.|||.|.|| ..|||||:||||.||||||||||||||||||||
Human   133 EGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQL 197

  Fly   198 ICEAYHIMQS-LGLSADQMADEFGKWNSAELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKG 260
            ||||||:|:. ||::.|:||..|..||..||||||||||.:|||::|..| :||.:|||:|||||
Human   198 ICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKG 262

  Fly   261 TGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLKGPSTKAQVANLTKFLDDIKHAL 325
            |||||||:||:|||||||||||||:||||:|||||:|||..||||.......:...||:||:.||
Human   263 TGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKAL 327

  Fly   326 YCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLD 390
            |.:||:||||||||:|:||.|..|.||||||||||||||||||||||.||||:...|||.|||||
Human   328 YASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLD 392

  Fly   391 DFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYEL 455
            ||||.|:|..|||||..|:...:.|||:|..:||||||||||...|||:|:||||||||||||||
Human   393 DFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYEL 457

  Fly   456 LGQEGQFHHTNWTGTGGNVSASTYQA 481
            |.:.|||.||||||.||.||:|:|.|
Human   458 LAKPGQFIHTNWTGHGGTVSSSSYNA 483

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.