Protein Alignment D2hgdh and Agps

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_445802.2
• Gene: Agps / 84114
• RGDID: 620364
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 137/585 - (23%)
• Similarity: 237/585 - (40%)
• Gaps: 117/585 - (20%)

  Fly    22 RRPITTTTITTTS---RTALAATYPAFATTVRTMAGSGAPIPELT--EITDNVQRGNYATLTDKD 81
            |.|::...:.|..   :..|........|:..::..|.|| |.:.  :....::..:.:...|.|
  Rat   129 RYPLSGLALPTLKDWIQNTLGVNLEHKTTSKPSINPSEAP-PSIVNEDFLQELKEAHISYSQDAD 192

  Fly    82 VAHFE---QLLGKNFVLTEDLEGYNICFLKRIRGNSKLVLKPGSTAEVAAILKYCNERRLAVVPQ 143
            ...|.   ..|.:.|:|.|.:       .:||   ..:|:.|....:|..|:....:..|.::|.
  Rat   193 DRVFRAHGHCLHEIFLLREGM-------FERI---PDIVVWPTCHDDVVKIVNLACKYNLCIIPI 247

  Fly   144 GGNTGLVGGSVPICDE----IVLSLARLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPL 204
            ||.|.:..|.:...||    |.|..:::|::|.|||....|.||||...::.:::.:|.|.....
  Rat   248 GGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGH 312

  Fly   205 DLGAKASCHIGGNVSTNAGGVRVVRYGNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLF 269
            :..:.....:||.:||.|.|::...|||:...|:.::.|...| |::..|...:.:||..:.|..
  Rat   313 EPDSLEFSIVGGWISTRASGMKKNVYGNIEDLVVHMKMVTPRG-VIEKSSQGPRMSTGPDIHHFI 376

  Fly   270 IGSEGTLGVVTKLSML---CPHSSRAVNVAFIGLNSFDDVLKTFVSAKRNLGEILSSCELIDERA 331
            :||||||||:|:.::.   .|...:..:|||.........|:..  ||:....  :|..|:|.
  Rat   377 MGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREI--AKQRCAP--ASIRLMDN-- 435

  Fly   332 LNTALEQFKF-----------LNSPISGFPFYMLIETSGSNGDH----------DEEKI----NQ 371
                 :||:|           ..|.:.||..:.:.:..|.:.:.          |.||:    .|
  Rat   436 -----QQFQFGHALKPQVSSIFTSFLDGFKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQ 495

  Fly   372 FIGDGMERGEIQDGTVTGDPGKVQEIWKIREMVPLGL----IEKSFCFKYDISLP---LRDF-YN 428
            ......:.|.:..|...|..|.:. .:.|..|..|||    :.:||    :.|.|   :.|. .|
  Rat   496 VYDIAAKFGGLAAGEDNGQRGYLL-TYVIAYMRDLGLEYYVVGESF----ETSAPWDRVIDLCRN 555

  Fly   429 IVDVMRERC-------GPLATV---------VCGYGHLGDSNLHLNVSCEEFNGEIYKRV-EPF- 475
            :.:.:|..|       .||:|.         .|.|.:..            ||   |:.: :|.
  Rat   556 VKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFA------------FN---YRGISDPLT 605

  Fly   476 VYEYTSKLK--------GSISAEHGIGFLKKDYLHYSKDPVAIGYMREMKKLLDPNSILNPYKVL 532
            |:|.|....        ||:|..||:|.|:|.:|..|...|..|.::.:|..:||::|.....:|
  Rat   606 VFEQTEAAARDEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPSNIFGNRNLL 670

  Fly   533  532
              Rat   671  670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	125/515 (24%)
		FAD_binding_4	115..252	CDD:279851	39/140 (28%)
		FAD-oxidase_C	291..531	CDD:280983	65/298 (22%)
Agps	NP_445802.2	GlcD	212..664	CDD:223354	119/493 (24%)
		FAD_binding_4	218..361	CDD:279851	39/143 (27%)
		FAD-oxidase_C	396..669	CDD:280983	66/303 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810