Protein Alignment D2hgdh and Gulo

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_071556.2
• Gene: Gulo / 60671
• RGDID: 620701
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 230
• Identity: 57/230 - (24%)
• Similarity: 99/230 - (43%)
• Gaps: 36/230 - (15%)

  Fly   119 KPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGGSVPICDEIVLSLARLNKVLSVDEVTGIAVVE 183
            :|.|..||..:|....|::..|...||  |.....:...|..::.:.::|:||.||:......||
  Rat    26 QPTSVEEVREVLALAREQKKKVKVVGG--GHSPSDIACTDGFMIHMGKMNRVLQVDKEKKQVTVE 88

  Fly   184 AGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVST---NAGGVRVVRYGNLHGSVLGVEAVLA 245
            ||.:|.:...:..|.||.:. :|||.:...:.|.:.:   |.|    :::|.|...|:.:..:.|
  Rat    89 AGILLADLHPQLDEHGLAMS-NLGAVSDVTVAGVIGSGTHNTG----IKHGILATQVVALTLMTA 148

  Fly   246 TGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVTKLSMLCPHSSRAVNVAFIGLNSFDDVLKTF 310
            .|:||:...:...|.......||     |.||::..:::.|      |....:...||...||
  Rat   149 DGEVLECSESRNADVFQAARVHL-----GCLGIILTVTLQC------VPQFHLQETSFPSTLK-- 200

  Fly   311 VSAKRNLGEILSSCELIDERALNTALEQFKFLNSP 345
                    |:|.:.:...:|:     |.|:||..|
  Rat   201 --------EVLDNLDSHLKRS-----EYFRFLWFP 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	57/230 (25%)
		FAD_binding_4	115..252	CDD:279851	37/135 (27%)
		FAD-oxidase_C	291..531	CDD:280983	13/55 (24%)
Gulo	NP_071556.2	FAD_lactone_ox	7..433	CDD:273751	57/230 (25%)
		FAD_binding_4	21..156	CDD:279851	37/136 (27%)
		ALO	180..438	CDD:281959	14/64 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810