Protein Alignment D2hgdh and dhcr24

DIOPT Version :10

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001008645.1
• Gene: dhcr24 / 494102
• ZFINID: ZDB-GENE-041212-73
• Length: 516
• Species: Danio rerio
• Alignment Length: 328
• Identity: 65/328 - (19%)
• Similarity: 107/328 - (32%)
• Gaps: 132/328 - (40%)

  Fly   161 VLSLARLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPL-----DL---------GAKAS 211
            :|.:....||:.|:.:..:..|.|   |.|      .:|.|:|:     ||         |.::|
Zfish   121 ILEVDTKRKVVRVEPLANMGQVTA---LLN------SIGWTLPVLPELDDLTVGGLVMGTGIESS 176

  Fly   212 CHIGGNVSTNAGGVRVVRYGNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLFIG---SE 273
            .||               ||......:..|.|||.|   .|:...:|:|:     .||..   |.
Zfish   177 SHI---------------YGLFQHICVAFELVLADG---SLVRCTEKENS-----DLFYAVPWSC 218

  Fly   274 GTLGVVTKLSMLCPHSSRAVNVAFIGLNSFDDVLKTFVSAKRNLGEILSSCELIDERALNTALEQ 338
            ||||.:....:....:.:.|.:.:..:...|.:.|.|.....|
Zfish   219 GTLGFLVAAEIRIIPAQKWVKLHYEPVRGLDAICKKFAEESAN---------------------- 261

  Fly   339 FKFLNSPISGFPFYMLIETSGSNGDHDEEKINQFIGDGME--RGE--IQDGTVT--GDPGKVQEI 397
                                         |.|||: :|::  |.|  |..|.:|  .:|.|...|
Zfish   262 -----------------------------KENQFV-EGLQYSRDEAVIMTGVMTDHAEPDKTNCI 296

  Fly   398 ------WKIREMVPLGLIEKSFCFKYDIS---LPLRDFYN---------IVDVMRERCGPLATVV 444
                  |..|.:       :||..:..::   :|||.:|:         :.|::.....||...|
Zfish   297 GYYYKPWFFRHV-------ESFLKQNRVAVEYIPLRHYYHRHTRSIFWELQDIIPFGNNPLFRYV 354

  Fly   445 CGY 447
            .|:
Zfish   355 FGW 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	77..533	CDD:440046	65/328 (20%)
dhcr24	NP_001008645.1	FAD_binding_4	<114..203	CDD:426326	25/108 (23%)