Protein Alignment D2hgdh and agps

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_956407.1
• Gene: agps / 386801
• ZFINID: ZDB-GENE-031118-14
• Length: 629
• Species: Danio rerio
• Alignment Length: 559
• Identity: 129/559 - (23%)
• Similarity: 227/559 - (40%)
• Gaps: 119/559 - (21%)

  Fly    56 GAPIPELTEITDNVQRGNYATLTDKDV--AHFEQLLGKNFVLTEDLEG----------YNICFLK 108
            ||.:...:..|.::   |.:.::..::  |..|.|.....:.:.|.|.          :.|..|:
Zfish   108 GASLQHKSPATSSL---NVSAVSPPNLNEAFSEDLKAAGLLASHDAEDRVFRAHGHCLHEIFALR 169

  Fly   109 --RIRGNSKLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGGSVPICDE------IVLSLA 165
              ||.....:|:.|...::|..|:....:..:.::|.||.|.:  .|...|.:      :.|..:
Zfish   170 EGRIGRVPDMVVWPSCHSDVEKIVDLACKHNVCLIPYGGGTSV--SSALECPQEETRCIVSLDTS 232

  Fly   166 RLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVSTNAGGVRVVRY 230
            ::|::|.:||....|.||||.|.::.:::..|.|.....:..:.....:||.|:|.|.|::...|
Zfish   233 QMNRILWIDEKNLTAHVEAGIIGQDLERQLNERGYCTGHEPDSMEFSSLGGWVATRASGMKKNIY 297

  Fly   231 GNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVTKLSML---CPHSSRA 292
            ||:...|:.::.|...| |::......:.:||..:.|..:||||||||||:::|.   .|...:.
Zfish   298 GNIEDLVVHIKMVTPRG-VIEKSCLGPRMSTGPDIHHFIMGSEGTLGVVTEVTMKIRPIPEYQKY 361

  Fly   293 VNVAFIGLNSFDDVLKTFVSAKRNLGEIL------SSCELIDERALNTALEQF------------ 339
            .:|.|          ..|......|.|:.      :|..|:|.       |||
Zfish   362 GSVVF----------PNFQQGVACLREVARQRCAPASIRLMDN-------EQFQFGHALKPQVSS 409

  Fly   340 ----------KFLNSPISGF-PFYMLIETSGSNGDH----DEEKINQFIGDGMERGEIQDGTVTG 389
                      ||..:...|| |.::.:.|....||.    ..||  |......:.|.:..|...|
Zfish   410 IFTSFLDGLKKFYITKFKGFDPHHLCVATLLFEGDRGKVLQHEK--QVYDIAAKFGGLAAGEDNG 472

  Fly   390 DPGKVQEIWKIREMVPLGL----IEKSFCFKYDISLPLRDFYNIVDVMRER----C-------GP 439
            ..|.:. .:.|..:..||:    |::||    :.|:|.....::...::||    |       .|
Zfish   473 QRGYML-TFVIAYLRDLGMDYYVIDESF----ETSVPWDRVLDLCRNVKERIIRECKERGVQFPP 532

  Fly   440 LATVVCGYGHLGDSNLHLNVSCEEF------NG-----EIYKRVEPFVYEYTSKLKGSISAEHGI 493
            |:|  |......|:.     :|..|      .|     .:|::||....|......||:|..||:
Zfish   533 LST--CRVTQTYDAG-----ACVYFYFAFNYRGLSDPVHVYEQVEHAAREEILANGGSLSHHHGV 590

  Fly   494 GFLKKDYLHYSKDPVAIGYMREMKKLLDPNSILNPYKVL 532
            |.|:|:::..|...|.:|.::.:|:.:||.:|.....:|
Zfish   591 GKLRKEWMKESVSGVGLGMIQSVKEFVDPQNIFGSRNLL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	123/526 (23%)
		FAD_binding_4	115..252	CDD:279851	36/142 (25%)
		FAD-oxidase_C	291..531	CDD:280983	64/298 (21%)
agps	NP_956407.1	GlcD	175..623	CDD:223354	114/481 (24%)
		FAD_binding_4	177..318	CDD:279851	36/143 (25%)
		FAD-oxidase_C	355..628	CDD:280983	65/303 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810