Protein Alignment D2hgdh and ADPS

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001188935.1
• Gene: ADPS / 36669
• FlyBaseID: FBgn0033983
• Length: 631
• Species: Drosophila melanogaster
• Alignment Length: 580
• Identity: 122/580 - (21%)
• Similarity: 209/580 - (36%)
• Gaps: 158/580 - (27%)

  Fly    31 TTTSRTALAATYPAFATTVRTMAGSGAPI---PELTEITDNVQRGNYATLTDKDVAHFEQLLGKN 92
            ||.....|..|||             .|:   |.|.|:....|....|...|:.|....|.|...
  Fly    96 TTKQYPQLPRTYP-------------RPVENAPFLHELKGTTQVDYSAEGIDRLVRCHGQTLNDI 147

  Fly    93 FVLTEDLEGYNICFLKRIRGNSKLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGG----- 152
            :.|          :..:.|....||:.|....||..:::..|:..:.:||.||.|.:.|.
  Fly   148 YSL----------WHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQ 202

  Fly   153 --SVPICDEIVLSLARLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPLDLGAKASCHIG 215
              |..||   .|..:::|::|.::........|:|.:.::.::..|..||||..:..:.....:|
  Fly   203 NESRMIC---ALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLG 264

  Fly   216 GNVSTNAGGVRVVRYGNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVT 280
            |.|:|.|.|::...|||:...|:.|..|..:| .|:...:..:.:.|....|:.:||||||||:|
  Fly   265 GWVATRASGMKKNVYGNIEDLVVRVRMVTPSG-TLERECSAPRVSCGPDFNHVILGSEGTLGVIT 328

  Fly   281 KL--------------SMLCPHSSRAV--------------------NVAFIGLNSFDDVLK--- 308
            ::              |:..|:..:.|                    |..|:    |...||
  Fly   329 EVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVARRRCQPASVRLMDNEQFM----FGQALKPEK 389

  Fly   309 ----TFVSAKR----------NLGEILSSCELID---------ERALNTALEQFKFLNSPISGFP 350
                :.|.|.:          :|.:|.::..|.:         |..:....|:|:       |||
  Fly   390 SWWASVVDAMKQRYVTSWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQ-------GFP 447

  Fly   351 FYMLIETSGSNGDHDE--EKINQFIGD-GMERGEIQDGTVTGDPGKVQEIWKIREMVPLGLIEK- 411
                  ..|.||:...  ..:..:|.| |:.:|.:.:...|..|      |....::...:.::
  Fly   448 ------AGGQNGERGYILTFVIAYIRDFGLHQGIVAESFETSVP------WDRCSLLCRSVKQRV 500

  Fly   412 -SFCFKYDISLPLRDFYNIVDVMRERCGPLATV---VCGYGHLGDSNLHLNVSCEEFNG------ 466
             |.|.|..|     ::|.|      .|....|.   .|.|.:.|            |..
  Fly   501 VSECSKRSI-----NYYTI------SCRVTQTYDAGACIYFYFG------------FRSTDVADP 542

  Fly   467 -EIYKRVEPFVYEYTSKLKGSISAEHGIGFLKKDYLHYSKDPVAIGYMREMKKLLDPNSI 525
             |:::.:|....:......||:|..||:|.::..:...:............|:.|||.:|
  Fly   543 VELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNI 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	108/523 (21%)
		FAD_binding_4	115..252	CDD:279851	39/143 (27%)
		FAD-oxidase_C	291..531	CDD:280983	52/296 (18%)
ADPS	NP_001188935.1	GlcD	152..612	CDD:223354	105/501 (21%)
		FAD_binding_4	159..300	CDD:279851	39/144 (27%)
		FAD-oxidase_C	337..608	CDD:280983	54/312 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740