Protein Alignment D2hgdh and ldhd

DIOPT Version :10

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_956167.1
• Gene: ldhd / 334208
• ZFINID: ZDB-GENE-030131-6140
• Length: 497
• Species: Danio rerio
• Alignment Length: 440
• Identity: 125/440 - (28%)
• Similarity: 207/440 - (47%)
• Gaps: 46/440 - (10%)

  Fly   116 LVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGGSVPICDEIVLSLARLNKVLSVDEVTGIA 180
            :|:.|.|..||:|:.|.|:..||.::|.|..|||.||...:...:..||.::.:|:.:.:.....
Zfish    72 VVVFPRSVEEVSALAKICHHYRLPIIPFGTGTGLEGGVSALQGGVCFSLRKMEQVVDLHQEDFDV 136

  Fly   181 VVEAGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVSTNAGGVRVVRYGNLHGSVLGVEAVLA 245
            .||.|...::.:...|:.||..|:|.||.||  :.|..:|:|.|...||||.:..:||.:|.|||
Zfish   137 TVEPGVTRKSLNSYLRDTGLWFPVDPGADAS--LCGMAATSASGTNAVRYGTMRENVLNLEVVLA 199

  Fly   246 TGQVLDLMSNF---KKDNTGYHMKHLFIGSEGTLGVVTKLSML---CPHSSRAVNVAFIGLNSFD 304
            .|.:|......   :|...||::.:||:|||||||::||.::.   .|.|..:...:|..:.|..
Zfish   200 DGTILHTAGKGRRPRKTAAGYNLTNLFVGSEGTLGIITKATLRLYGVPESMVSAVCSFPSVQSAV 264

  Fly   305 DVLKTFVSAKRNLGEILSSCELIDERALNTALEQFKFLNSPISGFPFYMLIETSGSNGDHDE--- 366
            |.....:.|    |..::..|.:|:..:| |..:|..|:..::...|   :|..||:...:|
Zfish   265 DSTVQILQA----GVPIARIEFLDDVMIN-ACNRFNNLSYAVTPTLF---LEFHGSSKSMEEQVS 321

  Fly   367 --EKINQFIGDGMERGEIQDGTVTGDPGKVQEIWKIRE---MVPLGLIEKSFCFKYDISLPLRDF 426
              |:|.:..|.       .|.....|......:||.|.   ...:.|......:..|:.:|:...
Zfish   322 VTEEITRDNGG-------SDFAWAEDEETRSRLWKARHDAWYAAMALRPGCKAYSTDVCVPISRL 379

  Fly   427 YNIV-----DVMRER-CGPLATVVCGYGHLGDSNLHLNVSCEEFNGEIYKRVEPFVYEYTSK--- 482
            ..|:     |::... .||:|      ||:||.|.|..:..:..:.:..:||..|......:
Zfish   380 PQIIVETKADLISNNITGPIA------GHVGDGNFHCLIVLDPNDPDEVQRVHSFTERLARRALA 438

  Fly   483 LKGSISAEHGIGFLKKDYLHYSKDPVAIGYMREMKKLLDPNSILNPYKVL 532
            :.|:.:.|||||..|:..|.....|:||..|:.:|..|||.:::||.|:|
Zfish   439 MDGTCTGEHGIGLGKRALLREELGPLAIEVMKGLKASLDPRNLMNPGKLL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	77..533	CDD:440046	125/440 (28%)
ldhd	NP_956167.1	GlcD	45..488	CDD:440046	124/438 (28%)