Protein Alignment D2hgdh and Gulo

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_848862.1
• Gene: Gulo / 268756
• MGIID: 1353434
• Length: 440
• Species: Mus musculus
• Alignment Length: 236
• Identity: 57/236 - (24%)
• Similarity: 99/236 - (41%)
• Gaps: 36/236 - (15%)

  Fly   115 KLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGGSVPICDEIVLSLARLNKVLSVDEVTGI 179
            ::..:|.|..||..:|....::...|...||  |.....:...|..::.:.::|:||.||:....
Mouse    22 EMYYQPTSVGEVREVLALARQQNKKVKVVGG--GHSPSDIACTDGFMIHMGKMNRVLQVDKEKKQ 84

  Fly   180 AVVEAGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVST---NAGGVRVVRYGNLHGSVLGVE 241
            ..||||.:|.:...:..:.||.:. :|||.:...:||.:.:   |.|    :::|.|...|:.:.
Mouse    85 VTVEAGILLTDLHPQLDKHGLALS-NLGAVSDVTVGGVIGSGTHNTG----IKHGILATQVVALT 144

  Fly   242 AVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVTKLSMLCPHSSRAVNVAFIGLNSFDDV 306
            .:.|.|.||:...:...|.......||     |.|||:..:::.|......:.      .||...
Mouse   145 LMKADGTVLECSESSNADVFQAARVHL-----GCLGVILTVTLQCVPQFHLLE------TSFPST 198

  Fly   307 LKTFVSAKRNLGEILSSCELIDERALNTALEQFKFLNSPIS 347
            ||          |:|.:   :|.....:  |.|:||..|.|
Mouse   199 LK----------EVLDN---LDSHLKKS--EYFRFLWFPHS 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	57/236 (24%)
		FAD_binding_4	115..252	CDD:279851	36/139 (26%)
		FAD-oxidase_C	291..531	CDD:280983	13/57 (23%)
Gulo	NP_848862.1	FAD_lactone_ox	7..433	CDD:273751	57/236 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810